Two new dimeric abietanoid peroxides with xanthine oxidase and ACE inhibitory activities from the bark of Cryptomeria japonica

Biogenetic and biomimetic synthesis of natural bisditerpenoids: hypothesis and practices

“…Five abietane-type diterpenoid homodimers with a peroxide linkage, 246–250 , were isolated from Cryptomeria japonica . 147,148 From the same plant, japonicinol A ( 251 ) is a heterodimeric analog of 246–250 bearing a peroxide linkage. 104 The first example of a biscembranoid connected by a peroxide group, bischerbolide peroxide ( 252 ), was isolated from the Formosan soft coral Sarcophyton cherbonnieri .…”