Two New Xanthones from Comastoma pulmonarium and Their Anti-Tobacco Mosaic Virus Activity

Hu, Qiu‐Fen; Wang, Xiaolong; Zeng, Wan-Li; Wang, Jin; Xu, Yongnan; Huang, Haitao; Li, Jing; Liu, Xin; Yang, Guangyu; Li, Xuemei; Zhang, Chengming; Li, Gang-Peng

doi:10.1007/s10600-019-02888-0

Cited by 2 publications

(1 citation statement)

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“…Aktivitas beragam dari derivate santon dipengaruhi oleh substitusi gugus fungsi pada kerangka trisikliknya (Jiang et al 2004). Santon telah dilaporkan memiliki aktivitas farmakologi yang baik sebagai antiinflamasi (Mohan et al 2018;Tewtrakul et al 2009), antibakteri (Iimuna et al 1996;Dharmaratne et al 2013;Suzy et al 2018), antijamur (Kaomongkolgit et al 2009), antivirus (Hu et al 2019), antidiabetes (Miura et al 2001;Nelli et al 2013;Sriyatep et al 2015and Trinh et al 2017), antikanker (Akao et al 2008Shan et al 2011;Orozko et al 2013;Victor et al 2014, Zhengxiang et al 2015and Wahyuni et al 2015and Ganogpichayagrai et al 2017, antitrombolitik (Yoo et al 2014), antiplatelet (Jantan et al, 2002) dan antikolesterol (Dachriyanus et al, 2006).…”

Section: Pendahuluanunclassified

Farmakokinetika dan Bioavailability Senyawa Golongan Santon Revew Komprehensif

Susanti

2019

jpfi

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The use of herbs for treating various ailment dates back several centuries. Evidence-based verification of the efficacy of Herbal medicines is still frequently lacking. Of particular interest is the question of bioavailability to assess to what degree and how fast compounds are absorbed after administration of herbal. Of further interest is the elucidation of metabolic pathways, and the assessment of elimination routes and their kinetics. These data become an important issue to link data from pharmacological assays and clinical effects. A better understanding of the pharmacokinetics and bioavailability of phytopharmaceuticals can also help in designing rational dosage regimens. To provide provide a detailed picture on ADME parameters (absorption, distribution, metabolism, and excretion) of some xanthone active compound, this article reviews the pharmacokinetic profile of 7 xanthones bioactive compound from the year 2009 onward.

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