Two novel stilbene phytoalexins from Arachis hypogaea

Aguamah, Grace E.; Langcake, P.; Leworthy, David P.; Page, Janet A.; Pryce, Robert J.; Strange, Richard

doi:10.1016/0031-9422(81)80044-1

Cited by 70 publications

(63 citation statements)

References 14 publications

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“…The T. versicolor activity of chlorophorin, however, was similar to the other extractives. Isoprenoid substitution has been reported to significantly increase stilbene fungal activity (Kindl 1985;Aguamah et al 1981), but our data suggest that the increased activity is limited to certain fungi. The mechanism by which stilbenes inhibit wood-decaying fungi is probably different for isoprenoid-vs. nonisoprenoid-s bstituted stilbenes, and thus our prior structure-activity relationship (SAR) results on the inactivity of 4 / -substituted stilbenes (Schultz et al 1990) are not applicable to this 4'-isoprenoid stilbene.…”

Section: Bioactivitiescontrasting

confidence: 70%

Durability of Angiosperm Heartwood: The Importance of Extractives

Schultz¹,

Harms²,

Fisher³

et al. 1995

HFSG

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Section: Bioactivitiescontrasting

confidence: 70%

Durability of Angiosperm Heartwood: The Importance of Extractives

Schultz¹,

Harms²,

Fisher³

et al. 1995

HFSG

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“…A 96 h time course per elicitor treatment was conducted including the following time points: 0, 0.5, 1, 3, 6,9,12,15,18,21,24,30,36,40,48,72 Extraction and Analyses of Stilbenoids from the Culture Medium. Stilbenoids were extracted from the medium of NaOAc-, H 2 O 2 -, and MeJA-treated hairy roots as described before.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Enhanced Production of Resveratrol, Piceatannol, Arachidin-1, and Arachidin-3 in Hairy Root Cultures of Peanut Co-treated with Methyl Jasmonate and Cyclodextrin

Yang

Fang

Nopo-Olazabal

et al. 2015

J. Agric. Food Chem.

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Peanut (Arachis hypogaea) produces stilbenoids upon exposure to abiotic and biotic stresses. Among these compounds, the prenylated stilbenoids arachidin-1 and arachidin-3 have shown diverse biological activities with potential applications in human health. These compounds exhibit higher or novel biological activities in vitro when compared to their nonprenylated analogues piceatannol and resveratrol, respectively. However, assessment of these bioactivities in vivo has been challenging because of their limited availability. In this study, hairy root cultures of peanut were induced to produce stilbenoids upon treatment with elicitors. Co-treatment with 100 μM methyl jasmonate (MeJA) and 9 g/L methyl-β-cyclodextrin (CD) led to sustained high levels of resveratrol, piceatannol, arachidin-1, and arachidin-3 in the culture medium when compared to other elicitor treatments. The average yields of arachidin-1 and arachidin-3 were 56 and 148 mg/L, respectively, after co-treatment with MeJA and CD. Furthermore, MeJA and CD had a synergistic effect on resveratrol synthase gene expression, which could explain the higher yield of resveratrol when compared to treatment with either MeJA or CD alone. Peanut hairy root cultures were shown to be a controlled and sustainable axenic system for the production of the diverse types of biologically active stilbenoids.

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“…Recently, three stilbene phytoalexins were isolated in this laboratory from peanut kernels exposed to their native microflora; two of the compounds were novel and one had been previously described (Aguamah et a!., 1981). These compounds have been assigned the trivial names arachidin I, I1 and I11 (Fig.…”

Section: Oh -Ohmentioning

confidence: 99%

“…All three peanut phytoalexins inhibited both germination and hyphal extension of A.Jauus in the pg ml-I range. Since peanut kernels are capable of synthesizing these compounds in the low mg g-' range (Aguamah et al, 1981), an investigation was begun into why A.Javus colonizes peanut kernels. There were differences between variouscultivars in the initial rateofaccumulation of phytoalexins in response to slicing and these differences correlated with their dry seed resistance to colonization by A.Javus.…”

Section: Phytoalexin Accumulation In Peanut Kernels After Woundingmentioning

confidence: 99%

Circumstantial Evidence for Phytoalexin Involvement in the Resistance of Peanuts to Aspergillus flavus

Wotton¹,

Strange²

1985

Microbiology

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Three stilbene phytoalexins, elicited by slicing and incubating imbibed peanut kernels under aerobic conditions, inhibited spore germination and hyphal extension of Aspergillus flavus with ED50 values in the range 4.9-12.8 micrograms ml-1. Phytoalexin yield was dependent on cultivar, conditions and duration of incubation after slicing, and crop history. The yield of phytoalexin from ten cultivars studied, after slicing and incubating at 25 degrees C for 24 h, ranged from 28 to 935 micrograms per g fresh weight and was negatively correlated with dry kernel colonization by A. flavus [r = -0.868 when plotted as 1n (phytoalexin concn) against 1n (percentage peanut colonization)]. When the incubation period was extended to 96 h there was no such correlation. Reduced phytoalexin yields were obtained when sliced kernels of one cultivar studied were incubated in water or at 37 degrees C, and no phytoalexin was obtained when the slices were incubated under nitrogen gas or frozen before aerobic incubation. Drought stress during pod development in four cultivars studied reduced phytoalexin yields of sliced kernels incubated at 25 degrees C for 24 h by 17-65% compared with non-stressed controls.

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Two novel stilbene phytoalexins from Arachis hypogaea

Cited by 70 publications

References 14 publications

Durability of Angiosperm Heartwood: The Importance of Extractives

Durability of Angiosperm Heartwood: The Importance of Extractives

Enhanced Production of Resveratrol, Piceatannol, Arachidin-1, and Arachidin-3 in Hairy Root Cultures of Peanut Co-treated with Methyl Jasmonate and Cyclodextrin

Circumstantial Evidence for Phytoalexin Involvement in the Resistance of Peanuts to Aspergillus flavus

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