2007
DOI: 10.1016/j.amjsurg.2006.08.078
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Two-phase scintigraphy with technetium 99m–sestamibi in patients with hyperparathyroidism due to chronic renal failure

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Cited by 17 publications
(11 citation statements)
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“…10,11 Nevertheless, few surgeons actually believe that preoperative imaging techniques can improve the success rate of first surgery in uremic SHPT. 12 Indeed, studies on the role of 99mTc sestamibi in SHPT have led to conflicting results [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] ; likewise for studies that have combined ultrasonography and sestamibi scintigraphy. [28][29][30][31][32] The present study aimed at assessing the sensitivity and specificity of the combination of high-resolution ultrasonography and 99mTc sestamibi dual-phase scintigraphy in the preoperative localization of PTG as well as at evaluating their usefulness in surgical decision-making in hemodialysis patients with SHPT referred for first parathyroid surgery.…”
mentioning
confidence: 99%
“…10,11 Nevertheless, few surgeons actually believe that preoperative imaging techniques can improve the success rate of first surgery in uremic SHPT. 12 Indeed, studies on the role of 99mTc sestamibi in SHPT have led to conflicting results [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] ; likewise for studies that have combined ultrasonography and sestamibi scintigraphy. [28][29][30][31][32] The present study aimed at assessing the sensitivity and specificity of the combination of high-resolution ultrasonography and 99mTc sestamibi dual-phase scintigraphy in the preoperative localization of PTG as well as at evaluating their usefulness in surgical decision-making in hemodialysis patients with SHPT referred for first parathyroid surgery.…”
mentioning
confidence: 99%
“…Prednosti scintigrafije PŽ ogledaju se u njenoj visokoj osetljivosti, do 97%, i specifičnosti, do 95% kod pHPT za solitarne adenome [19,20]. Kod primarne, sekundarne i tercijarne paratireoidne hiperplazije, osetljivost scintigrafije PŽ je manja i kreće se izmeĎu 15% i 60% [21]. Lažno negativni nalazi najčešće su uzrokovani malim adenomatoznim i hiperplastičnim PŽ.…”
Section: Introductionunclassified
“…Mogu biti podjednako zahvaćene sve žlezde, ali su najčešće asimetrično uvećane, uz postojanje "dominantne" žlezde. Manja veličina hiperplastično izmenjenih u odnosu na adenomatozno izmenjene PŽ, glavni su razlog manje osetljivosti scintigrafske detekcije hiperplazije [21,22,25,27,28,32]. U našoj studiji scintigrafija je lokalizovala najveću hiperplastičnu žlezdu u 100% slučajeva, dok je osetljivost za otkrivanje svih hiperplastično izmenjenih PŽ bila 70%.…”
Section: Introductionunclassified
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