Tympanometry and otoscopy prior to myringotomy: issues in diagnosis of otitis media

Finitzo, Terese; Friel-Patti, Sandy; Chinn, Kathleen; Brown, Orval E.

doi:10.1016/0165-5876(92)90136-d

Cited by 82 publications

(52 citation statements)

References 8 publications

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“…However, the evidence shows that expert assessors do not always agree, particularly for the diagnosis of OME. [13][14][15] There are no similar published studies for AOM or CSOM. A case could be made that a relatively unhurried examination of a series of stored images may be a better method of making a judgement or diagnosis, than when having sometimes fleeting views of a tympanic membrane and middle ear through an otoscope.…”

Section: Discussionmentioning

confidence: 90%

Validation of tele-otology to diagnose ear disease in children

Eikelboom

Mbao

Coates

et al. 2005

International Journal of Pediatric Otorhinolaryngology

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Section: Discussionmentioning

confidence: 90%

Validation of tele-otology to diagnose ear disease in children

Eikelboom

Mbao

Coates

et al. 2005

International Journal of Pediatric Otorhinolaryngology

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“…Otoscopy is very useful in diagnosing middle ear abnormalities when combined with tympanometry (Finitzo et al, 1992). To determine whether significantly different tympanometric measurements corresponded to middle ear abnormalities, we performed video otoscopy, histology, and ABR analysis on selected mice.…”

Section: Video Otoscopy Histological Analysis and Abr Measurementmentioning

confidence: 99%

Tympanometry assessment of 61 inbred strains of mice

et al. 2007

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Otitis media (OM) accounts for more than 20 million clinic visits in the United States every year. Resistance to antibiotics has hampered current management of the disease. Identification of genetic factors underlying susceptibility to OM is greatly needed in order to develop alternative treatment strategies. Genetically defined inbred mouse strains offer a powerful tool for dissecting genetic and environmental factors that may lead to OM in mice. Here, we report a study of middle ear function of 61 genetically diverse inbred strains of mice using tympanometry. Of the 61 inbred strains tested, the 129P1/ReJ, 129P3/J, 129S1/SvImJ, 129X1/SvJ, A/HeJ, BALB/cJ, BUB/BnJ, C57L/J, EL/SuzSeyFrkJ, FVB/NJ, I/LnJ, LP/J, NZB/BlNJ, PL/J and YBR/Ei strains exhibited tympanograms that were statistically different from other healthy strains according to parameters including middle ear pressure, volume and compliance. These differences are most likely the result of genetic factors that, when understood, will facilitate prevention and treatment of otitis media in humans. In addition, a negative correlation between age and compliance of the tympanic membrane was discovered. This is the first report to successfully use tympanometry to measure mouse middle ear function, which has been a challenge for the hearing research field because of the mouse's tiny ear size.

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“…When a non-suppurative effusion is present, it varies quantitatively and qualitatively. Smallvolume, clinically unapparent effusions may be found at tympanocentesis [Paradise et al, 1976;Orchik et al, 1978;Fiellau-Nikolajsen, 1983;Karma et al, 1989;Toner and Mains, 1990;Babonis et al, 1991;Finitzo et al, 1992;Ovesen et al, 1993;Sassen et al, 1994;van Balen and de Melker, 1994;Watters et al, 1997]. In OME, effusions may be serous or mucoid [Carrie et al, 1992]; the former are mucin poor and associated with less inflammation in terms of immunoglobulin and cytokine levels [Chung et al, 2002;Yabe et al, 2008] and leucocyte infiltration [Tanaka et al, 1986;Yoon et al, 1990] (and are more often of shorter duration [Yoon et al, 1990], unilateral, and in an older age group [Giebink et al, 1982a, b]).…”

Section: Pathological Analysesmentioning

confidence: 99%

Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

Bhutta¹

2014

Audiol Neurotol

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Otitis media (OM) represents a complex set of clinically defined disease phenotypes. Epidemiological and pathological data suggest that inflammation of the middle ear occurs on a continuum of disease. Here I review epidemiological data and apply mathematical modelling to better define the interrelation of OM phenotypes, including the relationship of upper respiratory tract infection to acute OM (AOM), of AOM to OM with effusion, and of recurrent OM to chronicity of effusion. I use these mathematical models to represent OM graphically as a ‘landscape of disease'. This novel nosology may enable clinicians and researchers to better conceptualise middle ear inflammation in its various forms, although the limits of its application are also discussed.

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Tympanometry and otoscopy prior to myringotomy: issues in diagnosis of otitis media

Cited by 82 publications

References 8 publications

Validation of tele-otology to diagnose ear disease in children

Validation of tele-otology to diagnose ear disease in children

Tympanometry assessment of 61 inbred strains of mice

Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

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