Type 2 Myocardial Infarction: Diagnostic and Therapeutic Difficulties in Modern Cardiology

Korzukhin, Artem Yu.; Yuldoshev, Javhar R.; Troshina, Alexandra A.; Khuramshina, Laysan R.; Guzarik, Victoria N.; Dyrnaeva, Alsu D.; Safin, Lenar F.; Nurislamov, Aizat F.; Enikeev, Ilnur M.; Shaizhanova, Albina A.; Natalenko, Anna A.; Nodirov, Mamudkhon N.

doi:10.17802/2306-1278-2023-12-3-84-97

Kompleks. probl. serdečno-sosud. zabol.

2023

DOI: 10.17802/2306-1278-2023-12-3-84-97

|View full text |Cite

Type 2 Myocardial Infarction: Diagnostic and Therapeutic Difficulties in Modern Cardiology

Artem Yu. Korzukhin,

Javhar R. Yuldoshev,

Alexandra A. Troshina

et al.

Abstract: Highlights• Diagnosis and management of type 2 myocardial infarction present significant challenges nowadays due to variety of its etiological factors and clinical manifestations. The correct and definitive identification of type 2 myocardial infarction is of paramount importance, since the treatment in most cases differs significantly from that of type 1 myocardial infarction.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Features of atherosclerotic lesions of the coronary arteries in patients with myocardial infarction and concomitant newly diagnosed hypothyroidism

Gridneva,

Chesnikova,

Khripun

et al. 2024

Med. vestn. Ûga Ross.

View full text Add to dashboard Cite

Objective: to assess the incidence of newly diagnosed subclinical and manifest hypothyroidism in patients with ST-segment elevation myocardial infarction (STEMI) and to identify angiographic features of coronary artery lesions in this combined pathology.Materials and methods: in all patients with STEMI, the level of thyroid-stimulating hormone (TSH) was determined, and thyroid function was assessed if the TSH level deviated from the norm. Stage I of the study included 441 patients, stage II included 133 patients with STEMI. Depending on the presence of newly diagnosed hypothyroidism, patients were divided into 3 groups: 1st — patients without hypothyroidism (n = 57), 2A group — with subclinical hypothyroidism (n = 42) and 2B group — with manifest hypothyroidism (n = 34). All patients underwent coronary angiography and percutaneous coronary intervention.Results: newly diagnosed hypothyroidism occurred in 27.44% of patients with STEMI: subclinical — in 19.73%, manifest — in 7.7% of cases. Patients with concomitant overt hypothyroidism had significantly more severe atherosclerotic lesions of the coronary arteries compared to patients without hypothyroidism.Conclusion: a high incidence of newly diagnosed hypothyroidism in patients with STEMI was established (27.44% of cases). Multivessel coronary lesions were recorded more often in patients with overt hypothyroidism than in patients with subclinical hypothyroidism and without hypothyroidism.

show abstract

Features of atherosclerotic lesions of the coronary arteries in patients with myocardial infarction and concomitant newly diagnosed hypothyroidism

Gridneva,

Chesnikova,

Khripun

et al. 2024

Med. vestn. Ûga Ross.

View full text Add to dashboard Cite

show abstract

Acute myocardial infarction in patients with concomitant hypothyroidism: clinical features and heart rate variability during inpatient treatment

Gridneva,

Chesnikova,

Safronenko

et al. 2024

jour

View full text Add to dashboard Cite

Objective: to evaluate the features of the clinical course, as well as heart rate variability (HRV) during inpatient treatment in patients with ST-segment elevation myocardial infarction (STEMI) and concomitant newly diagnosed hypothyroidism.Materials and methods: the study included 133 patients with STEMI aged 40 to 88 years who were admitted to the cardiology department. Depending on the presence of newly diagnosed hypothyroidism syndrome, all patients were divided into 3 groups: group 1 consisted of patients with STEMI without hypothyroidism syndrome (n=57), group 2A — patients with STeMI and subclinical hypothyroidism (n=42) and group 2B — patients with STeMI and manifest hypothyroidism (n=34). Clinical symptoms and complications in the acute period of MI were evaluated in all patients, and Holter ECG monitoring (XM ECG) was performed.Results: during hospital treatment, patients with concomitant manifest hypothyroidism showed more frequent development of cardiac arrhythmias such as paroxysmal atrial fibrillation (AF) (p<0.05), supraventricular extrasystole (NE), paroxysmal supraventricular tachycardia (LVT) (p<0,05). When assessing the risk of early complications in the acute period of MI, higher scores were recorded in patients with manifest hypothyroidism (p<0.05). The analysis of HRV indicators showed that in the studied patients with concomitant manifest hypothyroidism, despite the presence of an acute period of MI, activation of the parasympathetic link of the ANS (autonomic nervous system) prevails in the regulation of heart rhythm, unlike in patients of the control group and the group with subclinical hypothyroidism, in whom, on the contrary, the influence of the sympathetic link of the ANS prevails.Conclusion: during hospitalization, patients with manifest hypothyroidism were statistically significantly more likely to develop supraventricular cardiac arrhythmias, and a higher risk of cardiovascular complications in the acute period of MI was determined compared with both the control group and the group of patients with subclinical hypothyroidism. In patients with concomitant manifest hypothyroidism, the activation of the parasympathetic link of the ANS in the regulation of heart rhythm is more pronounced, in contrast to patients in the control group and the group with subclinical hypothyroidism, in whom, on the contrary, the influence of the sympathetic link of the ANS prevails.

show abstract

Features of early remodeling of the left heart in patients with acute myocardial infarction and concomitant hypothyroidism

Gridneva,

Chesnikova,

Khripun

et al. 2024

jour

View full text Add to dashboard Cite

Objective: to evaluate the features of structural and functional remodeling of the left heart during hospitalization in patients with ST-segment elevation myocardial infarction (STEMI) and concomitant newly diagnosed hypothyroidism. Materials and methods: the study included 133 patients with STEMI aged 40 to 88 years admitted to the Rostov Regional Clinical Hospital. All patients were divided into 3 groups depending on the newly diagnosed hypothyroidism: Group 1 (control) included patients with STEMI without hypothyroidism syndrome (n=57), Group 2A — patients with STEMI and subclinical hypothyroidism (n=42) and Group 2B — patients with STEMI and manifest hypothyroidism (n=34). Patient data, clinical symptoms, information on complications in the acute period of myocardial infarction, echocardiographic examination results were entered into a specially developed questionnaire. Results: patients with STEMI of all groups were found to have increased values of indexed LV ESV and LVM, decreased values of indicators characterizing myocardial contractility, as well as the presence of stage I LVDD. Patients with subclinical hypothyroidism were found to have statistically significantly higher values of the indexed LA volume than patients without hypothyroidism. The peculiarities of structural and functional remodeling of the heart in the presence of overt hypothyroidism include significantly higher linear and volumetric parameters of the LA (ILP and IOLP), a greater decrease in the contractility of the LV myocardium (lower values of SV, SI and IOC), a more pronounced impairment of diastolic properties of the myocardium (lower DT value) compared to the control group. Conclusion: in patients with STEMI and concomitant overt hypothyroidism, more pronounced remodeling of the left heart in conditions of acute myocardial injury (larger size and volume of the LA, more pronounced impairment of systolic and diastolic function of the LV).

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Type 2 Myocardial Infarction: Diagnostic and Therapeutic Difficulties in Modern Cardiology

Cited by 3 publications

References 49 publications

Features of atherosclerotic lesions of the coronary arteries in patients with myocardial infarction and concomitant newly diagnosed hypothyroidism

Features of atherosclerotic lesions of the coronary arteries in patients with myocardial infarction and concomitant newly diagnosed hypothyroidism

Acute myocardial infarction in patients with concomitant hypothyroidism: clinical features and heart rate variability during inpatient treatment

Features of early remodeling of the left heart in patients with acute myocardial infarction and concomitant hypothyroidism

Contact Info

Product

Resources

About