Über die Isolierung eines Metamorphose-Hormons der Insekten in kristallisierter Form

Butenandt, Adolf; Карлсон, П.

doi:10.1515/znb-1954-0601

Cited by 350 publications

(81 citation statements)

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“…The first ecdysteroids (α-ecdysone and 20E) were isolated by Butenandt and Karlson in 1954 [1]. Physiologically, they principally functioned as insectmolting hormones.…”

Section: Introductionmentioning

confidence: 99%

HPLC analysis and blood-brain penetration of 20-hydroxyecdysone diacetonide

Kalász

Hunyadi

Tekes

et al. 2017

Acta Chromatographica

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Summary. Blood-brain penetration of 20-hydroxyecdysone 2,3;20,22-diacetonide (20DA) has been scouted using chromatographic methods. In vivo experiments were performed by treating male Wistar rats intraperitoneally (i.p.) with a dose of 50 mg kg −1 20DA. Control experiment was done by using 20-hydroxyecdysone (20E). Definite brain penetration of 20DA was found by using high-performance liquid chromatography (HPLC), while 20E does not show this type of distribution.

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“…The first ecdysteroids (α-ecdysone and 20E) were isolated by Butenandt and Karlson in 1954 [1]. Physiologically, they principally functioned as insectmolting hormones.…”

Section: Introductionmentioning

confidence: 99%

HPLC analysis and blood-brain penetration of 20-hydroxyecdysone diacetonide

Kalász

Hunyadi

Tekes

et al. 2017

Acta Chromatographica

View full text Add to dashboard Cite

show abstract

“…The mass of this buffer (M buffer ) can be calculated to be the difference between the mass of the pellet (M pellet ) and the mass of the hemocyanin (M Hc ). 1 Although the hemocyanin should be pelleted quantitatively, some hemocyanin can be detected (Ͻ20%) spectroscopically in the supernatant. This may be due to the fact that a part of the hemocyanin is accidentally removed from the surface of the pellet while recovering the last aliquot of supernatant above the pellet.…”

Section: H]ecdysonementioning

confidence: 99%

“…Using Equation 2, the dissociation constant (K D ) of the hemocyanin-ecdysone complex, was determined to be 4.4 mM on 1 The abbreviation used is: Hc, hemocyanin.…”

Section: H]ecdysonementioning

confidence: 99%