UJI AKTIVITAS ANTIBAKTERI KRIM EKSTRAK HERBA PEGAGAN ( Centella asiatica (L.) Urban) Terhadap  Propionibacterium acne

Sukirawati, Sukirawati; Khouw, Habiba Syafitri

doi:10.59060/jurkes.v7i1.269

Cited by 2 publications

(2 citation statements)

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“…Gotu kola extract contains bioactive compounds such as asiaticoside, which has been found to inhibit the growth of Propionibacterium acnes, the bacteria responsible for acne (Budi & Rahmawati, 2020). Another study proved that a cream preparation of gotu kola extract with a concentration of 5% had an inhibition of 17.3 mm, the negative control (cream base) did not show inhibitory activity against bacterial growth (Sukirawati & Khouw, 2023). According to Soebagio et al (2020), the ethanol extract of gotu kola leaves at a concentration of 20% has an inhibition zone area against Propionibacterium acnes bacteria that has the same value as that of clindamycin (6.0755 cm2).…”

Section: Resultsmentioning

confidence: 99%

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2024

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Acne is an inflammatory skin condition caused by sebaceous follicles and characterized by skin inflammation in the form of a buildup of bacteria and oil that clogs pores and causes acne. Centella asiatica (L.) Urb., often known as gotu kola, has antibacterial properties that inhibit Propionibacterium acnes, thereby reducing papules, pustules, and nodules. Antioxidants, asiatic acid, and madecassic acid found in gotu kola (Centella asiatica (L.) Urb.) can treat wounds. Skin damaged by acne can be repaired and rejuvenated with gotu kola antioxidants, which also help collagen formation more quickly in the skin. This research aims to examine the ability of gotu kola (Centella asiatica (L.) Urb.) extract to inhibit acnecausing bacteria (Propionibacterium acnes) resulting from a literature review. This research method is a literature review or literature review. Research journals that met the inclusion criteria (activity test results suppressing bacterial growth activity) were collected, and a journal summary was made. A summary of the research journals is included in the table sorted by the year of publication of the journal. Based on the results of a literature review carried out by researchers, Gotu kola can be extracted using the maceration method by soaking the plant material in an extraction solvent such as ethanol or water for a specified time. This process was used to remove the active components from the plant material. The inhibition zone formed was evaluated to determine the effectiveness of the extracts or preparations containing gotu kola extract in preventing bacterial growth. Antibacterial power was tested using agar media inoculated with Propionibacterium acnes, and extracts or preparations were added using the diffusion method. From the literature review, it can be concluded that antioxidants and other bioactive substances contained in gotu kola extract can inhibit the growth of Propionibacterium acnes. This was shown based on the negative control not suppressing bacterial growth activity, while the cream containing gotu kola extract at a concentration of 5% had an inhibitory power of 17.3 mm.

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Section: Resultsmentioning

confidence: 99%

Untitled

2024

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Section: Resultsmentioning

confidence: 99%

REVIEW: A STUDY ON THE USE OF GOTU KOLA EXTRACT (Centella asiatica (L.) Urb.) AS A TREATMENT FOR ACNE

Ikasari,

Pebriani

2024

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Acne is an inflammatory skin condition caused by sebaceous follicles and characterized by skin inflammation in the form of a buildup of bacteria and oil that clogs pores and causes acne. Centella asiatica (L.) Urb., often known as gotu kola, has antibacterial properties that inhibit Propionibacterium acnes, thereby reducing papules, pustules, and nodules. Antioxidants, asiatic acid, and madecassic acid found in gotu kola (Centella asiatica (L.) Urb.) can treat wounds. Skin damaged by acne can be repaired and rejuvenated with gotu kola antioxidants, which also help collagen formation more quickly in the skin. This research aims to examine the ability of gotu kola (Centella asiatica (L.) Urb.) extract to inhibit acne-causing bacteria (Propionibacterium acnes) resulting from a literature review. This research method is a literature review or literature review. Research journals that met the inclusion criteria (activity test results suppressing bacterial growth activity) were collected, and a journal summary was made. A summary of the research journals is included in the table sorted by the year of publication of the journal. Based on the results of a literature review carried out by researchers, Gotu kola can be extracted using the maceration method by soaking the plant material in an extraction solvent such as ethanol or water for a specified time. This process was used to remove the active components from the plant material. The inhibition zone formed was evaluated to determine the effectiveness of the extracts or preparations containing gotu kola extract in preventing bacterial growth ...

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UJI AKTIVITAS ANTIBAKTERI KRIM EKSTRAK HERBA PEGAGAN ( Centella asiatica (L.) Urban) Terhadap Propionibacterium acne

Cited by 2 publications

References 7 publications

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REVIEW: A STUDY ON THE USE OF GOTU KOLA EXTRACT (Centella asiatica (L.) Urb.) AS A TREATMENT FOR ACNE

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