Ulcerated draining plaque below stoma

Cutaneous Intestinal Metaplasia With Adenocarcinoma Treated With Intralesional Fluorouracil

“…The cause is unknown, but possible triggers include chronic mechanical inflammation and direct seeding of mucosal cells into the peristomal skin during surgical procedures. Bile salts may also play a role by promoting cell migration …”

“…Clinical presentation ranges from a few pink or red discrete papules to larger plaques surrounding a stoma . Destruction of affected tissue and screening for malignant transformation is recommended .…”

“…Clinical presentation ranges from a few pink or red discrete papules to larger plaques surrounding a stoma . Destruction of affected tissue and screening for malignant transformation is recommended . Treatments include surgical stomal revision, electrosurgery, and clinical monitoring .…”

“…[2][3][4][5] Destruction of affected tissue and screening for malignant transformation is recommended. 2 Treatments include surgical stomal revision, electrosurgery, and clinical monitoring. [2][3][4][5] In this case, histology showing foci of adenocarcinoma with background metaplasia along with a negative ileoscopy support the notion that metaplasia may have progressed to cancer.…”