Ultra high pressure extraction (UHPE) of ginsenosides from Korean Panax ginseng powder

Shin, Jae-Sung; Ahn, Soon‐Cheol; Choi, Sung-Won; Lee, Dong‐Un; Kim, Byung-Yong; Baik, Moo-Yeol

doi:10.1007/s10068-010-0104-0

Cited by 36 publications

(20 citation statements)

References 9 publications

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“…[29] and Shin et al . [30]. Extraction of crude saponin from adventitious roots of different cell lines was conducted as follows.…”

Section: Methodsmentioning

confidence: 99%

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots

Zhang¹,

Bae²,

Boo³

et al. 2011

Journal of Ginseng Research

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With the purpose of improving ginsenoside content in adventitious root cultures of Korean wild ginseng (Panax ginseng Meyer), the roots were treated with different dosages of γ-ray (5, 10, 25, 50, 75, 100, and 200 Gy). The growth of adventitious roots was inhibited at over 100 Gy. The irradiated adventitious roots showed significant variation in the morphological parameters and crude saponin content at 50 to100 Gy. Therefore, four mutant cell lines out of the propagation of 35 cell lines treated with 50 Gy and 100 Gy were selected on the basis of phenotypic morphology and crude saponin contents relative to the wild type control. The contents of 7 major ginsenosides (Rg1, Re, Rb1, Rb2, Rc, Rf, and Rd) were determined for cell lines 1 and 3 from 100 Gy and lines 2 and 4 from 50 Gy treatments. Cell line 2 showed more secondary roots, longer length and superior growth rate than the root controls in flasks and bioreactors. Cell line 1 showed larger average diameter and the growth rate in the bioreactor was comparable with that of the control but greater in the flask cultured roots. Cell lines 1 and 2, especially the former, showed much more ginsenoside contents than the control in flasks and bioreactors. Therefore, we chose cell line 1 for further study of ginsenoside contents. The crude saponin content of line 1 in flask and bioreactor cultures increased by 1.4 and 1.8-fold, respectively, compared to the control. Total contents of 7 ginsenoside types (Rg1, Re, Rb1, Rb2, Rc, Rf, and Rd) increased by 1.8 and 2.3-fold, respectively compared to the control. Crude saponin and ginsenoside contents in the bioreactor culture increased by about 1.4-fold compared to that the flask culture.

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“…[29] and Shin et al . [30]. Extraction of crude saponin from adventitious roots of different cell lines was conducted as follows.…”

Section: Methodsmentioning

confidence: 99%

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots

Zhang¹,

Bae²,

Boo³

et al. 2011

Journal of Ginseng Research

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“…(Chen, Meng, Zhang, & Liu, ). High pressure extraction (HPE) has been recently applied to extract various compounds, such as polysaccharides from the Ligusticum rhizome (Liu et al, ), anthocyanins from black chokeberry (Grunovaitė, Pukalskienė, Pukalskas, & Venskutonis, ), ginsenosides from ginseng powder (Shin et al, ), rutin from Amaranthus leaves (Kraujalis, Venskutonis, Ibanez, & Herrero, ), flavonoids and phenolic compounds from Camellia leaf extracts (Joo et al, ) corilagin from the pericarp of longan fruit (Prasad, Yang, Zhao, Ruenroengklin et al, ), and various other bioactive materials from different plant parts, such as the extraction of green tea phenolic compounds and caffeine (Jun, ; Xi et al, ; Xi, Shen, Li, & Zhang, ), flavonoids from propolis (Shouqin, Jun, & Changzheng, ) and xanthohumol from hop (Santos et al, ). Studies have shown a number of advantages of HPE technique, such as shortened processing time, lower power consumption (Corrales et al, ; Jun, ; Liao, Liu, He, Chen, & Zhang, ), higher extraction yields, and fewer impurities in the extraction liquid over the other extraction methods.…”

Section: Introductionmentioning

confidence: 99%

High pressure extraction and its application in the extraction of bio‐active compounds: A review

Khan

Aslam

Makroo

2018

J Food Process Engineering

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Extraction of bio‐active compounds has become very important as these compounds show various characteristics which are beneficial to health, such as antioxidant, anti‐carcinogenic and antimicrobial properties. High pressure extraction (HPE) can be included among the recent and novel methods for extracting bioactive compounds from natural materials. The high pressure is applied to stimulate various phenomena (such as transition of phase from one form to another, change in reaction dynamics, change in molecular structure, etc.) which induces a reaction in a direction promoting a decrease in volume hence resulting in the enhancement of extraction efficiency. This article presents a comprehensive review of HPE and its applications in various food products and wastes. The review highlights that HPE is potential option for conventional extraction methods to meet the industrial demand. As most of the research has been conducted at laboratory scale level therefore recommendations for scaling up of the HPE process are made to evaluate the performance at commercial levels. Practical applications Extraction is considered to be a vital unit operation in downstream processes. However the conventional methods of extraction have various disadvantages viz. time and solvent consuming, energy deficient, poor extraction, risky to environment. High pressure extraction has a huge potential to partially or fully overcome these disadvantages. This review article presents the working mechanism and principle of HPE, and recent research conducted to evaluate the HPE process of potential bio‐active compounds from various plant and animal sources. HPE has been found to facilitate the recovery of these potential bio‐active compounds in their best natural form. Also it is recommended that HPE could be scaled up to make the extraction process relatively easy and efficient at commercial level.

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“…High pressure can enhance the mass transfer rate, increase solvent permeability in cells as well as secondary metabolite diffusion (Ahmed & Ramaswamy, 2006;Dornenburg & Knorr, 1993). Studies showed that UPE technique could shorten processing time, obtain higher extraction yield, and had no negative effect on the activity and structure of bio-active components (Corrales, Avelina, Peter, & Bernhard, 2009;Shin et al, 2010;Xi, 2006). Above all, this extraction technique could be operated at ambient temperature (Nagendra et al, 2010;Xi et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…Above all, this extraction technique could be operated at ambient temperature (Nagendra et al, 2010;Xi et al, 2010). Recently it had been successfully used for extraction of anthocyanins from grape skins (Corrales et al, 2009), ginsenosides from Korean panax ginseng powder (Shin et al, 2010), biologically active compounds from green tea leaves (Xi et al, 2010) and corilagin from longan fruit pericarp (Nagendra et al, 2010) and so on.…”

Section: Introductionmentioning

confidence: 99%

Ultrahigh pressure extraction as a tool to improve the antioxidant activities of green tea extracts

Deji

et al. 2011

Food Research International

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Ultra high pressure extraction (UHPE) of ginsenosides from Korean Panax ginseng powder

Cited by 36 publications

References 9 publications

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots

High pressure extraction and its application in the extraction of bio‐active compounds: A review

Ultrahigh pressure extraction as a tool to improve the antioxidant activities of green tea extracts

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Ultra high pressure extraction (UHPE) of ginsenosides from Korean Panax ginseng powder

Cited by 36 publications

References 9 publications

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (60Co) of Adventitious Roots

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (60Co) of Adventitious Roots

High pressure extraction and its application in the extraction of bio‐active compounds: A review

Ultrahigh pressure extraction as a tool to improve the antioxidant activities of green tea extracts

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Product

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Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots

Ginsenoside Production and Morphological Characterization of Wild Ginseng (Panax ginseng Meyer) Mutant Lines Induced by γ-irradiation (⁶⁰Co) of Adventitious Roots