Ultrasensitive microfluidic paper-based electrochemical/visual biosensor based on spherical-like cerium dioxide catalyst for miR-21 detection

Sun, Xiaolu; Wang, He; Jian, Yannan; Lan, Feifei; Zhang, Lina; Liu, Haiyun; Ge, Shenguang; Yu, Jinghua

doi:10.1016/j.bios.2018.01.025

Cited by 112 publications

(58 citation statements)

References 27 publications

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“…Paper-based substrates show an intrinsic versatility since different kind of paper can be used as suitable materials depending on the application, from printer paper [2,3], glossy brochure paper, newspaper, cardboard [4] to photopaper [5], and chromatographic paper [6]. Being a disposable material, paper-based sensors have proven their validity in studies of biological samples in laboratories, but they can show their usefulness in resource-limited situations owing to low-cost, robustness and ease-of-disposal, simply burning the device in presence of biological samples avoiding sterilization [7,8]. It is also possible to find their use in other sectors, like environmental monitoring, food and cosmetics industries [9,10].…”

Section: Introductionmentioning

confidence: 99%

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Serpelloni

Cantù

Borghetti

et al. 2020

Sensors

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Printed electronics is an expanding research field that can reach the goal of reducing the environmental impact on electronics exploiting renewable and biodegradable materials, like paper. In our work, we designed and tested a new method for fabricating hybrid smart devices on cellulose substrates by aerosol jet printing (AJP) and photonic curing, also known as flash lamp annealing (FLA), capable to cure low temperature materials without any damage. Three different cellulose-based materials (chromatographic paper, photopaper, cardboard) were tested. Multilayer capability and SMDs (surface mount devices) interconnections are possible permitting high flexibility in the fabrication process. Electrical and geometrical tests were performed to analyze the behavior of printed samples. Resulted resistivities are 26.3 × 10−8 Ω⋅m on chromatographic paper, 22.3 × 10−8 Ω⋅m on photopaper and 13.1 × 10−8 Ω⋅m on cardboard. Profilometer and optical microscope evaluations were performed to state deposition quality and penetration of the ink in cellulose materials (thicknesses equal to 24.9, 28.5, and 51 μm respectively for chromatographic paper, photopaper, and cardboard). Furthermore, bending (only chromatographic paper did not reach the break-up) and damp environment tests (no significant variations in resistance) where performed. A final prototype of a complete functioning multilayer smart devices on cellulose 3D-substrate is shown, characterized by multilayers, capacitive sensors, SMDs interconnections.

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Section: Introductionmentioning

confidence: 99%

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Serpelloni

Cantù

Borghetti

et al. 2020

Sensors

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“…In the presence of Lin, Au may form coordination complexes with sulfur through the Au/S covalent interactions. 22,23 As shown in Fig. 3 and S3 (ESI †), the chelation interaction may happen between Lin and Au in solution.…”

Section: Resultsmentioning

confidence: 96%

Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl₄and NaOH

Leng

et al. 2019

RSC Adv.

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“…Paper‐based microfluidics are mostly used in combination with colorimetric and electrochemical readout for detecting biomolecules . These devices are made of low‐cost bioactive papers such as nitrocellulose membranes (e.g., Whatman BA85 Protran) or cellulose‐based papers (e.g., chromatography paper) .…”

Section: Paper‐based Microfluidicsmentioning

confidence: 99%

Biofunctionalization of Glass‐ and Paper‐Based Microfluidic Devices: A Review

Shakeri

Jarad

Leung

et al. 2019

Adv Materials Inter

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Biofunctionalization of microchannels is of great concern in the fabrication of microfluidic devices. Different substrates such as glass slides, papers, polymers, and beads require different biofunctionalization approaches granting the utilization of microfluidics in several biomedical applications. Covalent immobilization of biomolecules inside the microchannels is achieved by chemical modification of the surface such as silanization or introducing different coupling agents. Although creating biointerfaces that are covalently bonded to the microchannel surface necessitates multiple steps of surface modification and incubation times, it bestows a robust biointerface capable of withstanding high shear stresses and harsh conditions without dissipating the biofunctionality. Regarding the applications that do not require robustness and long‐term stability, noncovalent attachment of biomolecules such as van der Waals and hydrophobic interactions are adequate to successfully create a functional biointerface. This review summarizes the various biofunctionalization approaches used in the most common microfluidic substrates: glass and paper. In addition, several biofunctionalization examples are proposed and described in detail along with their associated applications.

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Ultrasensitive microfluidic paper-based electrochemical/visual biosensor based on spherical-like cerium dioxide catalyst for miR-21 detection

Cited by 112 publications

References 27 publications

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl₄and NaOH

Biofunctionalization of Glass‐ and Paper‐Based Microfluidic Devices: A Review

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Ultrasensitive microfluidic paper-based electrochemical/visual biosensor based on spherical-like cerium dioxide catalyst for miR-21 detection

Cited by 112 publications

References 27 publications

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl4and NaOH

Biofunctionalization of Glass‐ and Paper‐Based Microfluidic Devices: A Review

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Product

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Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl₄and NaOH