Ultrasensitive Sandwich-Type Electrochemical Aptasensor for Dual Detection of Lung Cancer Biomarkers

Recent advancement in the detection of potential cancer biomarkers using the nanomaterial integrated electrochemical sensing technique: a detailed review

“…Jiang et al in 2023 fabricated an ultrasensitive sandwich type electrochemical aptasensor for dual lung cancer biomarker detection of NSE and epidermal growth factor receptor (EGFR) using the black phosphorus-gold nanocomposite (BP-AuNC). 186 BP-AuNC was synthesized using an in situ reduction process without using other reducing agents and the synthesized nanocomposite was decorated onto the working area of an electrode of a cloth substrate matrix and a three electrode system was fabricated by screen printing. This BP-AuNC provides good electrical conductivity and a large number of binding sites to capture the aptamer.…”