Ultrasonic Elastography Features of Phyllodes Tumors of the Breast: A Clinical Research

Abstract

The purpose of this study was to analyze the ultrasonic elastography features of phyllodes tumors of the breast comparing with fibroadenomas. A retrospective database was queried for the patients diagnosed as phyllodes tumors and fibroadenomas at Sun Yat-sen Memorial Hospital from January 2008 to August 2012. Three hundred and fifty lesions from 323 consecutive patients were included in the study. All the cases were examined by conventional ultrasonography and ultrasound elastography. Ultrasound elastography was used to calculate strain ratio of the lesions with bilateral breast tissue at the same depth as reference. There were 36 phyllodes tumors (27 benign, 8 borderline, 1 malignant) and 314 fibroadenomas (158 the pericanalicular type, 103 the intracanalicular type, 53 other special types). The strain ratio for phyllodes tumors (3.19±2.33) was significantly higher than for fibroadenomas (1.69±0.88) (p<0.05). The Spearman.s correlation coefficient between strain ratio of ultrasound elastography and pathological groups was significant, with a value of 0.17 (p<0.05). Ultrasound elastography could provide additional information to differentiate phyllodes tumors from fibroadenoma in breast.

Combination of shear-wave elastography and color Doppler: Feasible method to avoid unnecessary breast excision of fibroepithelial lesions diagnosed by core needle biopsy

“…These results are in accordance with the results of a previous study using strain elastography [19]. PTs are histologically characterized with more abundant and cellular stroma than FAs [1,5].…”

Ultrasound and elastography findings in phyllodes tumors of the breast

“…Literatürde FT'lerin elastografi bulgularını tanımlayan çok sınırlı sayıda çalışma bulunmaktadır (15,16) . Bu çalışmalarda, elastografide FT'lerin fibroadenomlardan daha sert yapıda olduğu ve BI-RADS 5 Lexicon sınıflamasına göre sert veya ara sertlikte kategorize edildiği bildirilmiştir (16) . Çalışmamızda, literatürden farklı olarak FT'lerin elastografik olarak çoğunlukla yumuşak veya ara sertlikte solid kitleler olarak izlendiğini gösterdik.…”

“…FT'lerin fibroadenomlardan ayırt edilebilmesinde görüntüleme yöntemleri tek başına yeterli olmamaktadır. Literatürde yayınlanan sınırlı sayıdaki çalışmada FT'lerin fibroadenomlardan daha sert kodlandığı bildirilse de karakteristik bir bulgu henüz tanımlanmamıştır (16) .…”

“…Başka bir çalışmaya göre, US ile kistik boşluklar malign FT'lerde benign FT'lerden daha sıktır (10) . Literatürde elastografinin benign FT'leri borderline ve malign FT'lerden ayırıma da katkı sağladığı bildirilmiştir (16) . Çalışmamızda, malign ve borderline tümörü olan birer olgu olduğu için istatiksel karşılaştırma yapılamadı.…”

Clinical value of ultrasonic elastography in diagnosing thyroid carcinoma

“…Thyroid cancer is a clinically common disease whose morbidity has increased in recent years [9]. Pathogenesis of thyroid cancer is often unobvious and can be divided into benign and malignant lesions.…”