Ultrastructural evaluation of parathyroid and ultimobranchial glands in iguanas with experimental nutritional osteodystrophy

Anderson, Marilyn P.; Capen, Charles C.

doi:10.1016/0016-6480(76)90102-7

Cited by 21 publications

(19 citation statements)

References 28 publications

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“…These changes in the experimental mice are thought to be in duced by stimulating the secretory process in most chief cells. These results are fairly con sistent with the observations which demon strate the increase in functional activity of the parathyroid gland [Melson, 1966;Capen and Rowland, 1968;Fetter and Capen, 1970;Yousliak and Capen, 1970;Furuta, 1971;Isono et al, 1971;Altendhr, 1972;Fujii and Isono, 1972;Isono and Shoumura, 1973;Anderson and Capen, 1976 ;Chan, 1977;Isono eta!., I976a,b;Takai, 1976;Coleman and Silbermann, 1978].…”

Section: Discussionsupporting

confidence: 78%

Effects of cadmium on the ultrastructure of the mouse parathyroid gland

Isono¹,

Shoumura²,

Ishizaki³

et al. 1979

Cells Tissues Organs

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Electron-microscopic studies were made on the parathyroid gland of cadmiumtreated mice. Most chief cells in treated mice were rich in free ribosomes and secretory granules compared to the control mice. In the parathyroid gland after 3 and 4 weeks of administration of cadmium, interdigitations between adjacent chief cells became more complex than in the control mice. In most chief cells of the parathyroid gland after 2, 3 and 4 weeks of administration of cadmium, the Golgi complexes associated with numerous prosecretory granules were better developed than in the control mice. These ultrastructural appearances suggest that parathyroid gland cellular activity was stimulated in response to cadmium treatment.

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Section: Discussionsupporting

confidence: 78%

Effects of cadmium on the ultrastructure of the mouse parathyroid gland

Isono¹,

Shoumura²,

Ishizaki³

et al. 1979

Cells Tissues Organs

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“…Only two parathyroids have been found by Anderson and Capen (1976) in the Iguana iguana, Underwood (cited by Clark, 1970) in Cyclura craniata and Cyclura caymanensis, and Adams (1953) in Crotaphytus collaris collaris.…”

Section: Ophidiamentioning

confidence: 95%

“…During summer, the parathyroids showed secretory activity by exhibiting narrow blood capillary spaces and very little degeneration of parenchymal cells (Akbarsha, 198513). Ultrastructural studies performed on the parathyroids of Iguana iguana revealed no changes (Anderson and Capen, 1976) which may be due to the constant experimental environment. Isono et al (1979) have found no ultrastructural differences in parathyroid glands of Japanese lizard Takydromus tachydromoides collected during spring or summer seasons.…”

Section: Seasonal Variationsmentioning

confidence: 96%

“…The long electron-dense cytoplasmic processes extend between adjacent parathyroid cells and contain scant endoplasmic reticulum, a small Golgi apparatus, and moderate numbers of mitochondria (Anderson and Capen, 1976). The parathyroid cells of Chamaeleon calcaratus were distinguished into light and dark chief cells (Pathan and Nadkarni, 1987a), the number of light cells being very small.…”

Section: Squamatamentioning

confidence: 99%

“…The parenchymal cells contained numerous free ribosomes and mitochondria, well-developed Golgi apparatus, a few lysosome-like bodies, some multivesicular bodies, and numerous lipid vacuoles (Anderson and Capen, 1976;Isono et al, 1979). The cisternae of the rough endoplasmic reticulum were distributed randomly in the cytoplasm.…”

Section: Squamatamentioning

confidence: 99%

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Morphology and physiological significance of parathyroid glands in reptilia

Srivastav

Sasayama

Suzuki

1995

Microscopy Res & Technique

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Adult reptiles possess one or two pairs of parathyroid glands that have been shown in many species to derive from the third and fourth pharyngeal pouches, respectively. Up to five pairs may develop during early embryonic life. Excess glands may involute during late embryogenesis. The location of the parathyroid glands differs in the various species. As a general rule, they lie just anterior to the heart, the anterior pair (parathyroid III) being associated with the carotid artery, the posterior pair (parathyroid IV) with the aortic arch. In snakes, however, the anterior pair (parathyroid III) is associated with the carotid artery near the angle of the jaw. As shown by light microscopy and, to a lesser extent, by electron microscopy, the parathyroid parenchyma comprises secretory cells which may form dark and light variants, occasional oxyphil cells, and stellate cells. They are arranged in cords separated by connective tissue containing a capillary network. Parathyroid secretory cells often form follicles which might be the result of degeneration. Degeneration may occur as a form of involution during winter in species undergoing seasonal changes. The product of parathyroid cells, the parathyroid hormone, is responsible for the maintenance of blood calcium concentration. The sites of action--bones, kidneys, intestine, endolymphatics, and dermal skeleton--are not well understood or not investigated. In some turtles, parathyroid hormone is not the (main) factor for the regulation of calcium homeostasis.

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Parathyroids and ultimobranchial bodies in monotremes

Haynes

1999

Anat. Rec.

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Only scant information is available in the scientific literature on the parathyroids and ultimobranchial bodies in the primitive mammals, the echidna (Tachyglossus aculeatus) and platypus (Ornithorhynchus anatinus). The major aim of this paper is to describe the morphology of the monotreme parathyroid gland and to compare it with parathyroids in mammals and reptiles. The gross anatomy and light microscopic structure of the ultimobranchial body, thymus, and thyroid are also given. Animals were dissected and routine light and electron microscopic techniques used to examine the microscopic morphology. The locations of parathyroid hormone, calcitonin and calcitonin gene-related peptide in tissue sections were identified by immunostaining. Monotremes have one pair of parathyroid glands located in the thorax and they are often associated with thymic tissue but never with the thyroid which is also present in the mediastinum. Ultimobranchial bodies are ventrolateral to the commencement of the trachea. Thymic lobules with Hassall's corpuscles are scattered in the fibrofatty tissue of the mediastinum and the ventral surface of the pericardium. Histologically, principal cells, water-clear cells, and non-secretory cells were identified in the parathyroid glands. Principal cells showed polarity and had microlamellar projections that formed intercellular canaliculi. Non-secretory cells had features similar to those of thymic epithelial reticular cells. Immunostaining of parathyroid hormone showed a diffuse distribution in parathyroid principal cells and none in ultimobranchial bodies. Identification of the ultimobranchial bodies was confirmed by immunostaining. The monotreme parathyroid gland, ultimobranchial bodies and thyroid show reptilian as well as mammalian features.

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Ultrastructural evaluation of parathyroid and ultimobranchial glands in iguanas with experimental nutritional osteodystrophy

Cited by 21 publications

References 28 publications

Effects of cadmium on the ultrastructure of the mouse parathyroid gland

Effects of cadmium on the ultrastructure of the mouse parathyroid gland

Morphology and physiological significance of parathyroid glands in reptilia

Parathyroids and ultimobranchial bodies in monotremes

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