Ultraviolet Light-Enhanced Visualization of Cutaneous Signs of Carotene and Vitamin a Dietary Deficiency

Abstract

Dietary deficiencies are multiple and some of them may induce specific changes in the skin biology and structure. Vitamin A deficiency is well identified as a cause of xerosis and follicular keratosis. Skin of the forehead and balding scalp was examined in 3 homeless alcoholic men who suffered from altered liver functions and denutrition including carotene and vitamin A deficiencies. The ultraviolet light-enhanced visualization (ULEV) method was used with a computer-assisted video camera equipped with an internal ultraviolet-emitting unit. Twenty healthy age- and phototype-matched men served as controls. Subclinical alterations of the stratum corneum and tiny follicular horny spikes at the skin surface were disclosed by ULEV. They were consistent with discrete flakiness on the forearms. By contrast, skin of the face and scalp showed follicular horny impactions corresponding to kerosis without any evidence for interfollicular xerosis. The skin condition was markedly improved after a 10-week dietary normalization. It is concluded that the ULEV method reveals some of the mildest and subclinical skin changes secondary to carotene and vitamin A deficiency. It could tentatively be used as a cheap and non-invasive aid in clinical screening programs among populations at risk.

The Conundrum of Skin Pores in Dermocosmetology

“…This seemingly mutual exclusion has not yet received an explanation. These stereotyped dots of subclinical perifollicular melanoderma were described in a series of studies [5, 6, 8, 9, 10]. Recently, other authors have reported seemingly identical features and coined them peripilar signs [13]failing to relate them to the melanin load in the perifollicular epidermis.…”

“…1) can be revealed on the facial skin and scalp of some subjects [5, 6, 8, 9, 10]. They are almost never associated with enlarged empty funnel-shaped pores.…”

“…1). Horny impactions in the infundibulum are clearly seen and recorded at standardized magnification [7, 9]. Empty pore widening is less identifiable.…”

“…The ultraviolet-light-enhanced visualization (ULEV) method [5, 6, 7, 8, 9, 10]is an improved variant of reflection ultraviolet photography [11, 12]. The procedure uses a computer-assisted CCD camera equipped with an internal UVA-emitting unit (Visioscan ® VC98, C + K Electronic, Cologne, Germany).…”

Skin in maturity: the endocrine and neuroendocrine pathways

“…This skin condition has many other origins [31] including vitamin A deficiency [32], climatic conditions [33], diabetes [34] and other endocrinopathies [5].…”