Uncaria tomentosa extract increases the number of myeloid progenitor cells in the bone marrow of mice infected with Listeria monocytogenes

Immunohematopoietic modulation by oral β-1,3-glucan in mice infected with Listeria monocytogenes

“…Several works have demonstrated that in listeriosis the ability of bone marrow to produce and mobilize granulocytes and macrophages to the site of infection is an essential component of the host defense during the early inflammatory response and consequently survival [17][18][19][20]37]. Studies from our laboratory have defined listeriosis as a useful experimental model to study the influence of various natural compounds and toxicants in the many components of the host immune responses involved in defense against L. monocytogenes, with special emphasis on the ability of hematopoietic tissues to produce and mobilize phagocytes [34][35][36]38,39]. It has been well demonstrated in the literature that during the early phase of Listeria infection there is a decrease in the number of granulocyte-macrophage colony-forming cells (CFU-GM) in the bone marrow and a massive migration to the spleen, leading to an extramedullar hematopoiesis with consequently splenomegaly and an increase in serum CSFs activity [24,36,38,39].…”

Prophylactic administration of Withania somnifera extract increases host resistance in Listeria monocytogenes infected mice

“…Several works have demonstrated that in listeriosis the ability of bone marrow to produce and mobilize granulocytes and macrophages to the site of infection is an essential component of the host defense during the early inflammatory response and consequently survival [24]. Studies from our laboratory have defined listeriosis as a useful experimental model to study the influence of various natural compounds and toxicants in the many components of the host immune responses involved in defense against L. monocytogenes, with special emphasis on the ability of hematopoietic tissues to produce and mobilize phagocytes [24][25][26][27][28]. It has been well demonstrated in the literature that during the early phase of Listeria infection there is a decrease in the number of granulocyte-macrophage colony-forming cells (CFU-GM) in bone marrow and a massive migration to the spleen, leading to an extramedullar hematopoiesis with consequently splenomegaly and an increase in serum CSFs activity [36,37].…”

“…Listeria monocytogenes has been extensively used as an experimental model to study the mechanisms involved in innate and cell-mediated antimicrobial defense. Following infection with L. monocytogenes, innate immune responses are rapidly triggered and are essential for host survival [24][25][26][27][28]. Early resistance to infection is attributed to the efficient mobilization of bone marrow-derived cells, particularly granulocyte/ macrophage cells, production of IFN-γ by natural killer cells and the resultant activation of macrophages [29].…”

Herbal Drugs in Chronic Fatigue Syndrome: An Overview

“…Cat's claw's immunostimulating properties enhance the function of white blood cells to attack and digest carcinogenic substances and harmful microorganisms that may inhibit the growth of cancer cells and tumours [55][56][57][58][59]. The pentacyclic alkaloids are responsible for the immune-strengthening effects, whereas the tetracyclic oxindole alkaloid rhynchophylline has an antihypertensive property that may be beneficial in preventing the risk of strokes and heart attacks by reducing heart rate, lowering blood pressure, increasing circulation, and lowering blood cholesterol levels [54].…”