Uncommon variants of fixed drug eruption

Agarwal, Akash; Das, Anupam; Panda, Maitreyee; Kumar, Piyush

doi:10.25259/ijdvl_502_2021

Cited by 4 publications

(3 citation statements)

References 47 publications

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“…Studies reported azithromycin-induced tense bullous lesions with surrounding erythema on the right side of the lower lip, upper lip, and near the angle of the mouth, Reported in India. [ 4 , 5 ] Multiple bullous lesions on the lower leg, left ankle, and genitalia associated with azithromycin intake had been reported. [ 6 ] A peculiar linear nondermatomal and nonblaschkoid clinical pattern located over the lower back midline due to azithromycin was reported.…”

Section: Discussionmentioning

confidence: 99%

Azithromycin-Induced Generalized Nonbullous Fixed-Drug Eruption

Adhimoolam,

Akili

2022

Journal of Research in Pharmacy Practice

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A BSTRACT Azithromycin-induced severe cutaneous reactions occur rare. We report a case of azithromycin-induced generalized nonbullous form of fixed-drug eruption (FDE). A 19-year-old male consulted the dermatology department for multiple painful oval-shaped, sharply defined, and hyperpigmented patches on his chest, abdomen, and upper limbs after consuming oral azithromycin tablets for his sore throat. The generalized nonbullous form of FDE was diagnosed, and the offending drug was stopped immediately. He was treated with antihistamines and steroids, and recovered on follow-up. This FDE is reported due to the spareseness of documentation from South India and to improve the awareness among the prescribing physicians about this severe cutaneous reaction (FDE) for a commonly used drug. This case report gives insight to the clinicians and health-care workers on rare side effects caused by the commonly used antimicrobial agent, azithromycin.

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Section: Discussionmentioning

confidence: 99%

Azithromycin-Induced Generalized Nonbullous Fixed-Drug Eruption

Adhimoolam,

Akili

2022

Journal of Research in Pharmacy Practice

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“…Covid-19 vaccines causing FDE are infrequently reported and widespread bullous variant and mucosal involvement are extremely rare. [ 1 ] Herein, we report a series of three cases who developed FDE ranging from classical to generalized bullous variant with mucosal involvement triggered by Covid-19 vaccination.…”

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confidence: 99%

“…Covid-19 vaccination induced FDE has been reported only in a handful of cases and is generally associated with a favorable prognosis. [ 1 ] Among various vaccines, the m-RNA vaccines are frequently reported as triggering agents. Covishield (recombinant ChAdOx1-S vaccine by AstraZeneca) and Covaxin (SARS-CoV-2 Antigen strain NIV-2020-770 by Bharat biotech) are the two most commonly administered vaccines against Covid-19 infection in the Indian subcontinent.…”

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confidence: 99%