“…Previous research has shown variation in prevalence of this gene among different racial/ethnic groups, in which a C to T mutation at nucleotide 677 is a risk factor for cardiovascular defects and NTDs (Franco, Araújo, Guerreiro, Elion, & Zago, ; Wilken et al, ). Additionally, sociodemographic factors such as nativity, individual socioeconomic status, and neighborhood were not further explored, but may also impact the prevalence of birth defects (Kirby et al, ; Shumate, Hoyt, Liu, Kleinert, & Canfield, ).…”