“…The analyses of these functions have led to important advances in our understanding of tissue development and homeostasis as well as pathologies, including tumorigenesis (for reviews, see Zhao et al, 2011;Patel and Edgar, 2014;Baillon and Basler, 2014). In Drosophila, analysis of the sizes and shapes of somatic clones affecting tumor suppressor and proto-oncogene activities is instrumental to understanding their contribution in tissue morphogenesis, organization and homeostasis (Resino et al, 2002;Baena-Lopez et al, 2005;Mao et al, 2011;Wartlick et al, 2011;Kuchen et al, 2012;Worley et al, 2013;Restrepo et al, 2014;Heemskerk et al, 2014). Accordingly, somatic mutant clones are essential for unveiling how tumor suppressor and proto-oncogene activities modulate tissue proliferation, growth, cell-cell interactions and cell competition (for a review, see Wagstaff et al, 2013).…”