The study aimed to trace the employability and professional development of Bachelor of Science in Biology graduates of a state university in Central Luzon, Philippines. Quantitative research design was utilized in tracing the employability and professional development of the total 97 graduates of BS Biology from 2008 to 2019. The study found that most of the graduates were permanently employed in a local government institution, specifically in the teaching profession, which is aligned with the objectives of the program. They also pursued graduate programs to expand their knowledge and skills needed for their respective careers. Graduates of the program were also satisfied with their current jobs and least likely to resign. Moreover, the study implied that the undergraduate program is relevant to the occupation of the graduates, especially for those who pursued careers in educational settings. The BS Biology undergraduate program of the state university contributes in the development of essential professional skills and competencies which are useful and relevant to the current job of its graduates.