Underwater- Versus Conventional Endoscopic Mucosal Resection of Large Sessile or Flat Colonic Polyps: Results of a Prospective Randomized Controlled Trial

Nagl, Sandra; Ebigbo, Alanna; Goelder, SK; Neuhaus, Lukas; Roemmele, Christoph; Weber, Tobias; Braun, Georg; Probst, Andreas; Schnoy, Elisabeth; Messmann, Helmut

doi:10.1055/s-0041-1724362

Cited by 1 publication

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“…En bloc resection rate was also significantly higher: 89% (95%CI 81-94%) vs. 75% (95%CI 65-83%), P=0.007. Two more RCTs from Europe were published as abstracts [ 22 , 23 ]. The first [ 22 ] randomized 58 and 59 patients with large sessile or flat colonic lesions to U-EMR or C-EMR, respectively.…”

Section: Underwater Emr (U-emr)mentioning

confidence: 99%

“…Two more RCTs from Europe were published as abstracts [ 22 , 23 ]. The first [ 22 ] randomized 58 and 59 patients with large sessile or flat colonic lesions to U-EMR or C-EMR, respectively. Preliminary results of this study showed similar en bloc resection rates (27.6% for U-EMR vs. 18.6% for C-EMR, P=0.27) and adverse events rates (15.5% for U-EMR vs. 16.9% C-EMR, P=0.1).…”

Section: Underwater Emr (U-emr)mentioning

confidence: 99%

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Modified endoscopic mucosal resection techniques for treating precancerous colorectal lesions

Tziatzios¹,

Gkolfakis

Papadopoulos

et al. 2021

aog

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Endoscopic mucosal resection (EMR) is a technique allowing efficacious and minimally invasive resection of precancerous lesions across the entire gastrointestinal tract. However, conventional EMR, involving injection of fluid into the submucosal space, is imperfect, given the high rate of recurrence of post-endoscopic resection adenoma, especially after piecemeal resection. In light of these observations, modifications of the technique have been proposed to overcome the weakness of conventional EMR. Some of them were designed to maximize the chance of en bloc resection—cap-assisted EMR, underwater EMR, tip-in EMR, precutting, assisted by ligation device—while others were designed to minimize the complications (cold EMR). In this review, we present their modes of action and summarize the evidence regarding their efficacy and safety.

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Section: Underwater Emr (U-emr)mentioning

confidence: 99%