Unilateral linear punctate palmoplantar keratoderma

Abstract

Punctate palmoplantar keratoderma (Brauer-Buschke-Fischer syndrome) is a rare entity. Among punctate keratoderma, the linear presentation is much rarer, and exact incidence is not known. Unilateral linear punctate palmoplantar keratoderma is not yet reported in the literature. Here we report a case 12-year-old child presented with asymptomatic linear punctate plaque on the left sole and hand; histology revealed hyperkeratotic epidermis without columns of parakeratosis or cornoid lamella.

Buschke-fischer-brauer keratoderma: Linear variety associated with Hodgkin′s lymphoma

“…Recently, a unilateral linear variety of punctate PPK has been described. [ 5 ] In our case as well, the linearity of the lesions could be well appreciated on the palms. Features that support the diagnosis of Type I hereditary punctate PPK in our patient include a family history suggestive of a possible autosomal dominant mode of inheritance spanning over three generations, clinical findings of multiple hyperkeratotic, crateriform papules and plaques involving the palms and soles, and absence of cornoid lamella on histopathological examination.…”

Focal acral hyperkeratosis with response to acitretin

“…Although acquired keratodermas have been linked to malignancies, especially gastrointestinal and pulmonary tumors 8 ; the specific subcategory of MPAs has not been reported to be associated with malignancy. Our patient was noted to have essential thrombocytosis undergoing active treatment.…”

“…For individuals with acquired FAH, adherence to age-appropriate cancer screening and consistent follow-up could be considered. 8 …”