Universal testing for coronavirus disease 2019 in pregnant women admitted for delivery: prevalence of peripartum infection and rate of asymptomatic carriers at four New York hospitals within an integrated healthcare system

Blitz, Matthew J.; Rochelson, Burton; Rausch, Andrew C.; Solmonovich, Rachel; Shan, Weiwei; Combs, Adriann; Nimaroff, Michael

doi:10.1016/j.ajogmf.2020.100169

Cited by 16 publications

(20 citation statements)

References 6 publications

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“…Early in the pandemic in New York City, non-Hispanic white residents were more likely to have testing performed even though the highest proportion of positive tests were recorded in predominantly non-white neighborhoods of lower socioeconomic status. 36 Epidemiologic studies in pregnancy, when aided by universal testing protocols, 27,37 provide a better understanding of the distribution of infection and disease in the larger population.…”

Section: Results In the Context Of What Is Knownmentioning

confidence: 99%

“…The Northwell Health Institutional Review Board approved the study as minimal-risk research using data collected for routine clinical practice and waived the requirement for informed consent. Some patients in this study were included in previous publications characterizing COVID-19 prevalence 1,27 and severity [28][29][30] during pregnancy.…”

Section: Study Population and Clinical Settingmentioning

confidence: 99%

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Social determinants of health and coronavirus disease 2019 in pregnancy

Prasannan

Rochelson

Shan

et al. 2021

American Journal of Obstetrics & Gynecology MFM

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Section: Results In the Context Of What Is Knownmentioning

confidence: 99%

Section: Study Population and Clinical Settingmentioning

confidence: 99%

Social determinants of health and coronavirus disease 2019 in pregnancy

Prasannan

Rochelson

Shan

et al. 2021

American Journal of Obstetrics & Gynecology MFM

Self Cite

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“…In one of the latter studies, the frequency of finding viral RNA in a respiratory specimen from presenting asymptomatic patients in Spain was only 0.5%, but yet overall, including known and symptomatic presentations, 8% of pregnant mothers were infected [ 175 ]. In New York, routine screening identified considerable asymptomatic infections [ 242 , 279 ]. The latter frequencies were occurring during peak pandemic.…”

Section: Maternal Management and Preventionmentioning

confidence: 99%

“…Regular entry viral screening has its merits, but such a routine will again depend on the prevalence of disease in the community [2,15,26,32,139,173,175,[279][280][281]. In one of the latter studies, the frequency of finding viral RNA in a respiratory specimen from presenting asymptomatic patients in Spain was only 0.5%, but yet overall, including known and symptomatic presentations, 8% of pregnant mothers were infected [175].…”

Section: Maternal Management and Preventionmentioning

confidence: 99%

A Comprehensive Analysis of Maternal and Newborn Disease and Related Control for COVID-19

Cimolai

2021

SN Compr. Clin. Med.

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The maternal-fetal/newborn unit is established at risk for COVID-19 infection. This narrative review summarizes the contemporary and cumulative publications which detail maternal infection, antenatal and newborn infections, and maternal/fetal/newborn management and prevention. There is a wide spectrum of maternal disease, but the potential for severe disease albeit in a minority is confirmed. COVID-19 carries risk for preterm delivery. Pregnant females can suffer multisystem disease, and co-morbidities play a significant role in risk. Congenital infection has been supported by several anecdotal reports, but strong confirmatory data are few. No typical congenital dysmorphisms are evident. Nevertheless, placental vascular compromise must be considered a risk for the fetus during advanced maternal infections. Clinical manifestations of newborn infection have been mild to moderate and relatively uncommon. Proven antiviral therapy is of yet lacking. The mode of delivery is a medical decision that must include patient risk assessment and patient directives. Both presymptomatic and asymptomatic mothers and offspring can complicate infection control management with the potential for spread to others in several regards. In the interim, infections of the maternal-fetal-newborn unit must be taken seriously both for the disease so caused and the potential for further dissemination of disease.

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“… 7 – 10 Universal SARS-CoV-2 screening of women in labor in the United States and United Kingdom (UK) has shown that, as in the general population, a large proportion of SARS-CoV-2–infected pregnant women are asymptomatic. 9 , 11 , 12 Among COVID-19 symptomatic women, fever and cough are the most observed symptoms in pregnancy. 10 , 13 , 14 However, pregnant women who are asymptomatic at the time of delivery may be at risk for clinical progression in the postpartum period, developing fever and respiratory symptoms.…”

mentioning

confidence: 99%

Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration

Nachega

Sam-Agudu

Budhram

et al. 2020

The American Journal of Tropical Medicine and Hygiene

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. In the African context, there is a paucity of data on SARS-CoV-2 infection and associated COVID-19 in pregnancy. Given the endemicity of infections such as malaria, HIV, and tuberculosis (TB) in sub-Saharan Africa (SSA), it is important to evaluate coinfections with SARS-CoV-2 and their impact on maternal/infant outcomes. Robust research is critically needed to evaluate the effects of the added burden of COVID-19 in pregnancy, to help develop evidence-based policies toward improving maternal and infant outcomes. In this perspective, we briefly review current knowledge on the clinical features of COVID-19 in pregnancy; the risks of preterm birth and cesarean delivery secondary to comorbid severity; the effects of maternal SARS-CoV-2 infection on the fetus/neonate; and in utero mother-to-child SARS-CoV-2 transmission. We further highlight the need to conduct multicountry surveillance as well as retrospective and prospective cohort studies across SSA. This will enable assessments of SARS-CoV-2 burden among pregnant African women and improve the understanding of the spectrum of COVID-19 manifestations in this population, which may be living with or without HIV, TB, and/or other coinfections/comorbidities. In addition, multicountry studies will allow a better understanding of risk factors and outcomes to be compared across countries and subregions. Such an approach will encourage and strengthen much-needed intra-African, south-to-south multidisciplinary and interprofessional research collaborations. The African Forum for Research and Education in Health’s COVID-19 Research Working Group has embarked upon such a collaboration across Western, Central, Eastern and Southern Africa.

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Universal testing for coronavirus disease 2019 in pregnant women admitted for delivery: prevalence of peripartum infection and rate of asymptomatic carriers at four New York hospitals within an integrated healthcare system

Cited by 16 publications

References 6 publications

Social determinants of health and coronavirus disease 2019 in pregnancy

Social determinants of health and coronavirus disease 2019 in pregnancy

A Comprehensive Analysis of Maternal and Newborn Disease and Related Control for COVID-19

Effect of SARS-CoV-2 Infection in Pregnancy on Maternal and Neonatal Outcomes in Africa: An AFREhealth Call for Evidence through Multicountry Research Collaboration

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