Unmasking dermatofibrosarcoma protuberans: Case report of an atypical presentation complicated by post-surgical excision

Zhou, YaQun; Chin, Justin; Strutin, Millard D.; Lomiguen, Christine M

doi:10.1016/j.ijscr.2020.03.020

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…Cases had been reported where Bednar tumor (DFSP) had been misdiagnosed as lipoma initially, and recurrence of the same mass after excision 15 – 17 . Similarly, in our case, the mass, which was initially misdiagnosed and treated as lipoma, recurred and then later diagnosed as Bednar tumor.…”

Section: Discussionmentioning

confidence: 99%

Bednar’s tumor at right shoulder in an adult male: a case report of a rare entity

Acharya,

Yadav,

Chetry

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction and Importance: Bednar tumor a rare variant of Dermatofibrosarcoma Protuberans is a tumor with low malignant potential. Owing to limited studies, the pathogenesis and risk factor of this tumor are not clearly understood. The tumor extends from the epidermis to dermal layers and even affects the surrounding bone. Here we present a case of a 48-year-old male with Bednar tumor which was successfully managed by wide local excision and flap repair. Case Presentation: Our patient presented to the hospital after the reappearance of mass ,six years after excision of the previously misdiagnosed lipoma. Vitals and systematic examination were normal. Local examination revealed an oval shaped mass with a glistening surface on the right shoulder. The patient underwent wide excision and skin flap surgery for the treatment, and the diagnosis was confirmed through histopathological examination and immunohistochemistry for the CD34 marker. Clinical Discussion: Bednar tumor is an infrequent skin tumor linked to genetic anomalies and is one of the rare variants (<0.1%) of skin tumors). Diagnosis can be done by histopathological examination (HPE) and CD34 marker positivity via immunohistochemistry (IHC). This tumor is mistaken for lipoma, leading to recurrent growth post-excision,. Tumor demands broader resection due to high chances of re-occurrence. Although Mohs Micrographic Surgery is the ideal approach, its limited availability in resource-constrained settings prompts alternative strategies. Conclusion: This case highlights the challenges of diagnosis, the rarity of the condition, and the need for vigilant follow-up due to the tumor’s propensity for recurrence.

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Section: Discussionmentioning

confidence: 99%

Bednar’s tumor at right shoulder in an adult male: a case report of a rare entity

Acharya,

Yadav,

Chetry

et al. 2024

Annals of Medicine &Amp; Surgery

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“…His acute symptoms should have warranted greater scrutiny in the context of overall health such that new atrial fibrillation would likely not be the primary cause of bilateral saddle pulmonary embolisms. Physicians must remain vigilant and detail-oriented when assessing patients with cardiovascular symptoms such as the ones described in this case report [18][19][20]. Further studies are needed to better screen and understand the disease progression for PAS.…”

Section: Discussionmentioning

confidence: 99%

Clinical Detection of Primary Pulmonary Angiosarcoma

Khalid

Khan

Lomiguen

et al. 2021

Cureus

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Pulmonary angiosarcomas (PAS) are rare malignant vascular tumors that due to their aggressive and metastatic nature, are often diagnosed at a late stage, resulting in a poorer prognosis. Here we present a 53-year-old male who was initially found to have recurring episodes of dyspnea and syncope, with initial workup showing bilateral saddle pulmonary embolisms on computerized tomography, presumed secondary to newly discovered atrial fibrillation with sinus node dysfunction. Further investigation over subsequent months and subsequent biopsy of a potential lung mass ultimately revealed pulmonary angiosarcoma of the spindle cell line. This case emphasizes findings in the current literature, which reveal the time between the onset of symptoms and definitive diagnosis ranges from two to six months, with a median survival time of seven months or two months, with solitary lesions or multiple lesions at the time of diagnosis, respectively. With the limited incidence of PAS, this case suggests benefits in the development of screening and detection criteria for earlier detection and treatment.

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