Unprotected left main intervention for surgery-ineligible patients with coronary artery disease—Usefulness of micro-CT images for stent

Sueta, Daisuke; Arima, Yuichiro; Hokimoto, Seiji; Mukunoki, Toshifumi; Tabata, Noriaki; Akasaka, Tomonori; Sato, Takahiro; Otani, Jun; Ogawa, Hisao

doi:10.1016/j.ijcard.2016.07.049

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…Identifying the tissue coverage was feasible and precise with micro-CT. This high-resolution imaging technique is still emerging in the cardiac field but has shown relevant applications in mapping valve and coronary calcification [ 17 – 20 ], to simulate coronary stent expansion [ 21 – 23 ] and to study cardiac and valve morphology [ 24 – 27 ]. Although in-vivo applications are limited by the high dose of radiation, the development of contrast agents (iodine agents, solutions of tungsten or barium ions) has enabled a reduction of exposure time [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Assessment of Nit-Occlud atrial septal defect occluder device healing process using micro-computed tomography imaging

Perdreau¹,

Jalal²,

Walton³

et al. 2023

PLoS ONE

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After percutaneous implantation of a cardiac occluder, a complex healing process leads to the device coverage within several months. An incomplete device coverage increases the risk of device related complications such as thrombosis or endocarditis. We aimed to assess the device coverage process of atrial septal defect (ASD) occluders in a chronic sheep model using micro-computed tomography (micro-CT). After percutaneous creation of an ASD, 8 ewes were implanted with a 16-mm Nit-Occlud ASD-R occluder (PFM medical, Cologne, Germany) and were followed for 1 month (N = 3) and 3 months (N = 5). After heart explant, the device coverage was assessed using micro-CT (resolution of 41.7 μm) and was compared to histological analysis. The micro-CT image reconstruction was performed in 2D and 3D allowing measurement of the coverage thickness and surface for each device. Macroscopic assessment of devices showed that the coverage was complete for the left-side disk in all cases. Yet incomplete coverage of the right-side disk was observed in 5 of the 8 cases. 2D and 3D micro-CT analysis allowed an accurate evaluation of device coverage of each disk and was overall well correlated to histology sections. Surface calculation from micro-CT images of the 8 cases showed that the median surface of coverage was 93±8% for the left-side disk and 55±31% for the right-side disk. The assessment of tissue reactions, including endothelialisation, after implantation of an ASD occluder can rely on in vitro micro-CT analysis. The translation to clinical practice is challenging but the potential for individual follow-up is shown, to avoid thrombotic or infective complications.

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Section: Discussionmentioning

confidence: 99%

Assessment of Nit-Occlud atrial septal defect occluder device healing process using micro-computed tomography imaging

Perdreau¹,

Jalal²,

Walton³

et al. 2023

PLoS ONE

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Current clinical applications and potential perspective of micro-computed tomography in cardiovascular imaging: A systematic scoping review

Papazoglou

Karagiannidis

Moysidis

et al. 2021

Hellenic Journal of Cardiology

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Volumetric Tissue Imaging of Surgical Tissue Specimens Using Micro–Computed Tomography: An Emerging Digital Pathology Modality for Nondestructive, Slide-Free Microscopy—Clinical Applications of Digital Pathology in 3 Dimensions

Papazoglou

Karagiannidis

Liatsos

et al. 2022

American Journal of Clinical Pathology

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Objectives Micro–computed tomography (micro-CT) is a novel, nondestructive, slide-free digital imaging modality that enables the acquisition of high-resolution, volumetric images of intact surgical tissue specimens. The aim of this systematic mapping review is to provide a comprehensive overview of the available literature on clinical applications of micro-CT tissue imaging and to assess its relevance and readiness for pathology practice. Methods A computerized literature search was performed in the PubMed, Scopus, Web of Science, and CENTRAL databases. To gain insight into regulatory and financial considerations for performing and examining micro-CT imaging procedures in a clinical setting, additional searches were performed in medical device databases. Results Our search identified 141 scientific articles published between 2000 and 2021 that described clinical applications of micro-CT tissue imaging. The number of relevant publications is progressively increasing, with the specialties of pulmonology, cardiology, otolaryngology, and oncology being most commonly concerned. The included studies were mostly performed in pathology departments. Current micro-CT devices have already been cleared for clinical use, and a Current Procedural Terminology (CPT) code exists for reimbursement of micro-CT imaging procedures. Conclusions Micro-CT tissue imaging enables accurate volumetric measurements and evaluations of entire surgical specimens at microscopic resolution across a wide range of clinical applications.

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Unprotected left main intervention for surgery-ineligible patients with coronary artery disease—Usefulness of micro-CT images for stent

Cited by 3 publications

References 22 publications

Assessment of Nit-Occlud atrial septal defect occluder device healing process using micro-computed tomography imaging

Assessment of Nit-Occlud atrial septal defect occluder device healing process using micro-computed tomography imaging

Current clinical applications and potential perspective of micro-computed tomography in cardiovascular imaging: A systematic scoping review

Volumetric Tissue Imaging of Surgical Tissue Specimens Using Micro–Computed Tomography: An Emerging Digital Pathology Modality for Nondestructive, Slide-Free Microscopy—Clinical Applications of Digital Pathology in 3 Dimensions

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