Unsteady Disposable Flow Tracking Using Discrete Phase Model

Zielińska, Monika; Sitko, Adam

doi:10.1080/01457632.2021.1875165

Cited by 1 publication

(1 citation statement)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Its main advantages include the capability to study the trajectories and behaviors of particle flow in microfluidic devices, as well as complex interactions, for example, among blood cells. However, it is a computationally intensive method compared to conventional approaches and requires rigorous control in the discretizations between different phases (assumptions and simplifications) [37,38].…”

Section: Numerical Setupmentioning

confidence: 99%

Numerical Model Validation of the Blood Flow through a Microchannel Hyperbolic Contraction

Barbosa,

Dueñas-Pamplona,

Abreu

et al. 2023

Micromachines

View full text Add to dashboard Cite

A computational fluid dynamics (CFD) model of blood flow through hyperbolic contraction with a discrete phase model (DPM) was experimentally validated. For this purpose, the positions and velocities of red blood cells (RBCs) flowing in a microchannel with hyperbolic contraction were experimentally assessed using image analysis techniques, and were subsequently compared with the numerical results. The numerically and experimentally obtained velocity fields were in good agreement, with errors smaller than 10%. Additionally, a nearly constant strain rate was observed in the contraction region, which can be attributed to the quasilinear increase in the velocity along the hyperbolic contraction. Therefore, the numerical technique used was validated due to the close similarity between the numerically and experimentally obtained results. The tested CFD model can be used to optimize the microchannel design by minimizing the need to fabricate prototypes and evaluate them experimentally.

show abstract

Section: Numerical Setupmentioning

confidence: 99%