Unveiling the functional components and anti-Alzheimer's activity of Koelreuteria elegans (Seem.) A.C. Sm. using UHPLC-MS/MS and molecular networking

Abstract

The metabolomic profiles of Koelreuteria elegans leaf and fruit methanol extracts using UHPLC-MS/MS analysis aided by molecular networking were explored. Both extracts reduced all the examined markers of inflammation and neurodegeneration in the injured streptozotocin (STZ)-induced AD mice.