Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning

Laher, Abdullah E.; Goldstein, Lara Nicole; Wells, Mike; Dufourq, Nicholas; Moodley, Pramodhini

doi:10.1016/j.afjem.2012.10.002

Cited by 9 publications

(6 citation statements)

References 9 publications

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“…They were able to monitor blood levels of ethanol and ethylene glycol in their patient. Laher et al [16] have used oral ethanol to treat three cases of ethylene glycol poisoning in Africa. Target ethanol concentration in such treatment is set at 100–150 mg/dl [1].…”

Section: Discussionmentioning

confidence: 99%

“…Detailed medical history is not always available due to the altered mental status of some patients at the time of presentation. In all cases with high anion gap metabolic acidosis and high osmolar gap, ethylene glycol poisoning must be considered [12, 16] unless there is any other definite cause suggested. Estimation of blood levels of ethylene glycol is not a readily available facility in the Indian scenario, so we need to rely more on strong index of suspicion, routine laboratory investigations, and clinical findings.…”

Section: Discussionmentioning

confidence: 99%

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Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol

Achappa

Madi

Kanchan

et al. 2019

Case Reports in Medicine

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Ethylene glycol poisoning is not uncommon in India. The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. A 70-year-old female presented to our hospital with ataxia after ingestion of ethylene glycol. The reported case describes the management of ethylene glycol poisoning using oral ethyl alcohol as an alternative to the recommended intravenous ethyl alcohol and fomepizole that are not available for use in India. The need for high degree of clinical suspicion, targeted investigations, and early instigation of treatment is of prime importance in cases of ethylene glycol poisoning as it can lead to long-term complications or even death.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol

Achappa

Madi

Kanchan

et al. 2019

Case Reports in Medicine

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“…False declaration associated with wine is a major issue of concern [ 20 , 21 , 22 ]. Adulteration of alcohol includes the non-disclosed use of ethylene glycol and methanol to fortify (raise the alcohol level) and/ or improve taste [ 23 , 24 , 25 , 26 ]. However, despite improved detection methods [ 27 , 28 , 29 ], the adulteration of alcohol products remains a concern at local, national and international scales.…”

Section: Illicit Alcohol Productionmentioning

confidence: 99%

“…In their research from 1992 to 2001 in Turkey, Yayci et al [ 33 ] note a gender influence with methanol poisoning, with men having the predominant fatalities (89.1%) compared to females (10.9%). In Africa, methanol poisoning from illicit alcohol production and sale is a particular health concern [ 23 , 38 , 39 , 40 ]. In 1963 in Spain, methanol was used to adulterate mixed alcohol liqueurs, and this incident led to 51 deaths [ 41 ].…”

Section: Illicit Alcohol Productionmentioning

confidence: 99%

Illicit Alcohol: Public Health Risk of Methanol Poisoning and Policy Mitigation Strategies

Manning

Kowalska

2021

Foods

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Illicit (unrecorded) alcohol is a critical global public health issue because it is produced without regulatory and market oversight with increased risk of safety, quality and adulteration issues. Undertaking iterative research to draw together academic, contemporary and historic evidence, this paper reviews one specific toxicological issue, methanol, in order to identify the policy mitigation strategies of interest. A typology of illicit alcohol products, including legal products, illegal products and surrogate products, is created. A policy landscape matrix is produced that synthesizes the drivers of illicit alcohol production, distribution, sale and consumption, policy measures and activity related signals in order to inform policy development. The matrix illustrates the interaction between capabilities, motivations and opportunities and factors such as access, culture, community norms and behavior, economic drivers and knowledge and information and gives insight into mitigation strategies against illicit alcohol sale and consumption, which may prove of value for policymakers in various parts of the world.

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“…This accessibility combined with its sweet taste makes it a fairly common overdose agent, both in cases of accidental (especially pediatric) ingestions and in suicide (15). Home alcohols for recreational purposes are commonly adulterated with EG to improve their taste and "sting" (16).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

The effect of antifreeze (ethylene glycol) on the survival and the life cycle of two species of necrophagous blowflies (Diptera: Calliphoridae)

et al. 2018

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Entomotoxicology involves the analysis of the presence and the effects of toxicological substances in necrophagous insects. Results obtained by entomotoxicological studies may assist in the investigation of both the causes and the time of death of humans and animals. Ethylene glycol (EG) is easy to purchase, sweet and extremely toxic. It may be consumed accidentally or purposefully, in an attempt to cause death for suicidal or homicidal intent. Several cases report fatalities of humans and animals. The present study is the first to examine the effects of EG on the survival, developmental rate and morphology of two blowfly species, (Diptera: Calliphoridae) typically found on corpses and carcasses: Lucilia sericata (Meigen) and L. cuprina (Wiedemann). Both species were reared on substrates (beef liver) spiked with three different concentrations of EG that could cause death in either a human or cat: 1/2LD (T1), LD (T2), 2LD (T3), in addition to a control treatment (C) with no EG. Results of this research show that: a) both species are unable to survive if reared on a food substrate spiked with the highest concentration of EG (T3), while lower and medium concentrations (T1, T2) affect, but not prevent, the survival and the completion of the life cycle of such species; b) adults of L. sericata eclose only in C and T1, while adults of L. cuprina in both C, T1, T2; however, c) the developmental time of both species reared in T1 and T2 is statistically slower than the control; d) the body length of the immatures of both of the species reared in T1 and T2 is statistically smaller than the control.

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Unwell after drinking homemade alcohol – A case of ethylene glycol poisoning

Cited by 9 publications

References 9 publications

Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol

Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol

Illicit Alcohol: Public Health Risk of Methanol Poisoning and Policy Mitigation Strategies

The effect of antifreeze (ethylene glycol) on the survival and the life cycle of two species of necrophagous blowflies (Diptera: Calliphoridae)

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