Update on Image-Guided Percutaneous Ablation of Breast Cancer

Fleming, Margaret M.; Holbrook, Anna I.; Newell, Mary S.

doi:10.2214/ajr.16.17129

Cited by 47 publications

(27 citation statements)

References 74 publications

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“…Ultrasound-guided percutaneous ablation procedures, including cryoablation, irreversible electroporation, laser therapy, microwave ablation, radiofrequency ablation, and high-intensity focused ultrasound, of benign and malignant breast lesions that are 2 cm or less in size are also being performed [35]. These ultrasound-guided ablation techniques are particularly appealing for patients who are not surgical candidates; however, identifying the group of patients best suited for percutaneous ablation procedures is evolving [35].…”

Section: Ultrasound Guided Interventional Breast Proceduresmentioning

confidence: 99%

“…These ultrasound-guided ablation techniques are particularly appealing for patients who are not surgical candidates; however, identifying the group of patients best suited for percutaneous ablation procedures is evolving [35]. While many of these percutaneous ablation techniques can be performed with local anesthesia alone, both radiofrequency ablation and high-intensity focused ultrasound must be performed with sedation and may be performed with MRI guidance instead of ultrasound guidance [35].…”

Section: Ultrasound Guided Interventional Breast Proceduresmentioning

confidence: 99%

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Breast Ultrasound Past, Present, and Future

Rapelyea¹,

Marks²

2018

Breast Imaging

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This chapter will review the utilization of breast ultrasound for screening and diagnostic purposes. Currently, ultrasound is primarily used to investigate palpable lesions in women less than 30 years old, to provide further characterization of abnormal mammographic findings, and to guide invasive breast interventions. Innovations in ultrasound technology have improved the detection and diagnosis of breast cancer. Computer-aided detection (CAD), elastography, quantitative breast ultrasound technology, and ultrasound contrast agents (microbubbles) were developed to improve diagnostic accuracy. These advancements have the potential to impact overall survival by detecting cancers that are smaller and less aggressive.

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Section: Ultrasound Guided Interventional Breast Proceduresmentioning

confidence: 99%

Section: Ultrasound Guided Interventional Breast Proceduresmentioning

confidence: 99%

Breast Ultrasound Past, Present, and Future

Rapelyea¹,

Marks²

2018

Breast Imaging

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“…Thermal ablation achieves rapid progress in the treatment of tumor in multiple organs including the liver, kidney, lung, thyroid, pancreas, breast, and others [7][8][9][10][11]. However, unlike their wide application in the liver and kidney, ablation techniques are a relatively new minimally invasive treatment for breast lesions.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound-guided percutaneous microwave ablation of central intraductal papilloma: a prospective pilot study

Meng

et al. 2019

International Journal of Hyperthermia

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Background: Central intraductal papilloma (IDP) has a low risk of cancer evolution; therefore, surgical treatment of IDP is controversial. We sought to validate ultrasound (US)-guided percutaneous microwave ablation (MWA) for minimally invasive treatment of IDP. Methods: Thirteen women with central IDP, including six with nipple discharge, underwent US-guided core needle biopsy and MWA from December 2016 to November 2017. Lesions histologically diagnosed as benign IDP were included. The hydro-dissection technique was used to protect the nipple during the entire ablation procedure. We evaluated and recorded data of complete ablation, volume reduction, and complications. Results: MWA was successfully performed in all patients, with 100% complete ablation, assessed by magnetic resonance imaging or contrast-enhanced US. Mean tumor size was 13.5 ± 4.1 (7.0-20.0) mm; the mean ablation time was 1.4 (0.7-10.3) min. At the median 13.7-month follow-up, mean lesion sizes at 3, 6, and 12 months after MWA were all significantly smaller than that at baseline. Total volume reduction rates were 52.3 ± 18.2% (range, 24.2-81.8%), 72.6 ± 23.1% (range, 39.4-95.9%), and 92.9 ± 7.5% (range, 75.0-100%) at 3-, 6-, and 12-month follow-up, respectively, with significant differences (p < .01). Three lesions with diameters 7 mm, 9 mm, and 12 mm disappeared completely at 3, 6, and 6 months after MWA, respectively, on US imaging. Nipple discharge disappeared immediately after MWA. Cosmetic effects were reported as excellent by all patients and no complications were observed. Conclusion: US-guided MWA of central IDP proved feasible and effective, with considerable volume reduction and satisfactory cosmetic outcomes.

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“…Cryoablation is the process by which cell death is achieved by creating freezing temperatures and inducing cell injury and ischemia with cell death occurring via necrosis and apoptosis . Currently, cryoablation is used a safe and effective treatment for breast fibroadenomas and is used elsewhere in the body for treatment of liver, prostate, and kidney tumors .…”

mentioning

confidence: 99%

“…Advantages of cryoablation include the ability to perform this procedure under local anesthesia and on an outpatient basis. It is well tolerated, produces good cosmetic results, and is a promising alternative for patients who otherwise would undergo a lumpectomy or who are not surgical candidates …”

mentioning

confidence: 99%

Successful cryoablation of breast cancer

Swintelski

Plaza²

2018

Breast J

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The current standard of care for screen-detected breast cancers is surgical excision. Cryotherapy is a promising non- surgical alternative treatment for these cancers and is performed under local anesthesia as an outpatient, circumventing the risks that come with an operation. New research also shows promising results for the treatment of breast cancer when cryotherapy is combined with immune modulation as it may help prevent tumor recurrence. We herein report a case of breast cancer treated successfully with cryoablation. A brief literature review of cryoablation as a treatment for breast cancer is added.

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Update on Image-Guided Percutaneous Ablation of Breast Cancer

Cited by 47 publications

References 74 publications

Breast Ultrasound Past, Present, and Future

Breast Ultrasound Past, Present, and Future

Ultrasound-guided percutaneous microwave ablation of central intraductal papilloma: a prospective pilot study

Successful cryoablation of breast cancer

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