Update on the Diagnosis and Management of Helicobacter pylori Infection in Adults

Abstract

Treatment of Helicobacter pylori infection is becoming increasingly challenging due largely to the rising rates of antimicrobial resistance and to the relative complexity of treatment regimens. If a reliable test to assess the antimicrobial sensitivity/resistance of H. pylori was readily available, treatment would be more focused and-presumably-more effective. However, antimicrobial sensitivity testing is difficult to obtain in most parts of the United States. Therefore, physicians have to rely on clinical judgment in selecting treatment regimens for their infected patients. The aims of this review are to summarize recent treatment recommendations and to examine available evidence for how we might improve on our current treatment selections. Information on this review is directed primarily toward physicians practicing in the United States.

The Association betweenHelicobacter pyloriInfection and Chronic Hepatitis C: A Meta-Analysis and Trial Sequential Analysis

“…Some of the included studies detected and diagnosed H. pylori infection via the serology method, whereas others used PCR-based methods. Usually, the serology method is less sensitive and specific [ 35 ]. Meanwhile, both H. pylori and H. hepaticus belong to the Helicobacter genus [ 36 ].…”

Estrategias terapéuticas para Helicobacter pylori en Colombia

“…Si hay una indicación de hacer endoscopia digestiva superior, adicional a la búsqueda de H. pylori, o si se requiere evaluar el estado de la mucosa gástrica, se prefieren los métodos invasivos con toma de biopsia para prueba de ureasa rápida, el estudio histológico, el cultivo o las pruebas moleculares, según disponibilidad. De lo contrario, el diagnóstico se hará con métodos no invasivos como la prueba de antígenos fecales con anticuerpos monoclonales o la prueba de urea en el aliento (8) .…”

The Use of Proton Pump Inhibitors and Prescription Pattern by Practicing Physicians at an Academic Hospital

“…Specialty professional organizations recommend that people take the lowest eff ective dose possible to achieve the desired therapeutic result when using proton pump inhibitors to treat gastroesophageal refl ux disease long-term [12] . In the United States, the Food and Drug Administration advises that no more than three 14-day treatment courses should be used in one year [13] .…”