Update on the sudden hearing loss

Bullo, Federica; Tzamtzis, S; Tirelli, Gian Carlo

doi:10.4103/0971-7749.117462

Cited by 5 publications

(8 citation statements)

References 23 publications

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“…10 All our patients presented within 72 hours of the symptoms and it has been concluded by Bullo et al that delay in starting treatment is considered as a poor prognostic factor. 11 In a study by Battaglia et al, they conclude that combined ITSI and oral steroid therapy is superior to oral therapy alone. 12 Which we also conclude.…”

Section: Discussionmentioning

confidence: 99%

A polydrug regime for treatment of sudden sensorineural hearing loss

Killera

Kauser

2020

Int J Otorhinolaryngol Head Neck Surg

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Sudden sensorineural hearing loss (SSNHL) is a very frightening and incapacitating event and it impairs the patient's quality of life. Steroids are considered the first line of treatment. Intratympanic dexamethasone produces a significantly higher perilymph concentration of steroids. The aim of our study was to assess the efficacy of multi-drug regimen in the management of SSNHL, to analyse the recovery and to assess use of intratympanic steroid injections (ITSI) as a primary treatment. This is a prospective study presenting as a case series of 5 cases of SSNHL. Our treatment included intratympanic steroids, oral steroids, antiplatelet drugs, rheological-agents and neuro vitamins. Complete recovery was seen in 2 (40%), partial recovery in 2 (40%), 1 patient was lost to follow up. In the patient with bilateral SSNHL, the ITSI was administered in the right ear only; which showed a significant improvement. SSNHL is described as a decline in hearing of 30 dB or more, on 3 or more frequencies over 3 days or less, with tinnitus and ear fullness. Early presentation and intervention within 72 hours is the ideal treatment. Since viral infections and vascular compromise are considered as probable theories for SSNHL, steroids, with anticoagulants, antiplatelet and rheological-agents are used as an effective therapy. Our study shows that a multi-drug treatment of SSNHL can be much more effective than a single drug treatment. We also conclude that using intratympanic steroid injections have a greater improvement as seen in the case of bilateral SSNHL.

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Section: Discussionmentioning

confidence: 99%

A polydrug regime for treatment of sudden sensorineural hearing loss

Killera

Kauser

2020

Int J Otorhinolaryngol Head Neck Surg

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“…Routine laboratory evaluation has low diagnostic yield and should only performed in case clinical suspicion [12]. It has seen that severe hearing loss has poor prognostic factor [13]. Treatment of SSNHL is a subject of debate.…”

Section: Discussionmentioning

confidence: 99%

Sudden sensorineural hearing loss in children: Our experiences in tertiary care teaching hospital of eastern India

Swain¹,

Sahu²,

Choudhury³

2018

polp

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Aim of the study: Sudden sensorineural hearing loss (SSNHL) is an uncommon clinical entity in children. The etiopathogenesis, clinical profile and management are not well understood and the incidence is not well known in medical literature. The goal of this study is to evaluate prevalence, etiology, treatment and outcome of SSNHL in the pediatric patients. Material and methods: We had undertaken a retrospective study of the children below 18 years of age with SSNHL treated between July 2014 to August 2017. The data assessed were age, sex, clinical manifestations, onset of hearing loss, audiological profile, other diagnostic tools, treatment and outcome. Results: The average age of the children presenting with SSNHL is 10.43 years (1-18 years). Twelve patients (6 right and 6 left) had unilateral hearing loss and 5 patients had bilateral hearing loss. Hearing loss ranges from profound (52.94%) to mild and unknown etiology in 70.58% and viral 29.41%. Hearing was completely improved in 5 cases (29.41%), partially improved in 8 cases (47.05%) and no improvement in 3 cases (17.64%). When comparing oral with oral plus intratympanic (IT) steroid, hearing output is stastically significant (p = 0.04020) with 95% confidential level is 0.69 to 0.02 and t = 2.1381. Conclusions: The exact incidences of SSNHL in pediatric age groups are not established in medical literature. Pediatric patients are usually delayed presentations and associated with unknown etiology in majority of cases. SSNHL has serious impact on life and it should be follow up for preventing morbidities and for starting rehabilitation program as early as possible.

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“…De acordo com a audiometria, pode-se dividir a gravidade do déficit auditivo em quatro graus, que consistem em leve (para perda de 20-40dB), médio (41-60 dB), moderado (61-70 dB), severo (71-90 dB) e profundo (maior que 90 dB) (10) . O primeiro exame audiométrico do paciente após a sintomatologia, demonstrou limiar auditivo de 75dB, 80dB, 70dB, 70dB e 70dB nas frequências 0,5 Hz, 1Hz, 2Hz, 3Hz, 4KHz, respectivamente, na OD configurando-se como SS de grau severo, confirmando a hipótese diagnóstica.…”

Section: Discussionunclassified

“…Apesar do grande número de publicações acerca da SS, nenhum tratamento específico demostrou eficácia comprovada e desse modo, a terapia com corticoides continua sendo a mais recomendada por ter os melhores resultados (10) , assim como existem evidências que sugerem que o uso corticosteroide pode bloquear a via da NF-kb, apoiando e justificando o seu uso na SS (20) .…”

Section: Discussionunclassified

“…A perda auditiva súbita é uma emergência otorrinolaringológica que requer tratamento imediato. Entretanto, mesmo depois da realização de vários estudos, nenhum tratamento apresentou eficácia comprovada (10) . Portanto, estudos como meta análise e revisão sistemática se fazem necessários para orientar o tratamento, já que esse é duvidoso e incerto (11,12) .…”

Section: Introductionunclassified

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Surdez súbita em paciente em uso de tadalafil: um relato de caso clínico

Assunção

Marques

2018

cmbio

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Introdução: A Surdez Súbita (SS) é uma emergência médica de baixa prevalência, porém com potencial de perda auditiva irreversível para o paciente. Possui diversos e ainda incertos mecanismos etiopatológicos. Recentemente a literatura vem trazendo a associação da SS com a classe dos inibidores da fosdodiesterase-5 (IPDE-5), a qual inclui medicamentos para tratamento de impotência sexual. Objetivo: Relatar caso clínico de paciente idoso que apresentou SS após fazer uso de medicamento da classe dos IPDE-5, pesquisando na literatura qual a provável fisiopatologia. Materiais e Métodos: Trata-se de estudo qualitativo, descritivo do tipo relato de caso clínico, realizado através da coleta de dados do prontuário médico, que foram comparados com literatura especializada. Resultado: Paciente masculino, 72 anos, engenheiro, procurou atendimento referindo hipoacusia e plenitude aural à direita notados subitamente há três dias. Relata ter feito uso de Tadalafil 5mg, anteriormente aos sintomas. Anamnese e exame físico direcionaram para hipótese diagnóstica de SS, de modo que exames complementares foram solicitados. À audiometria evidenciou-se perda auditiva sensorioneural moderada a severa em orelha direita. Após tratamento com prednisolona oral e mesilato de codergocrina, paciente apresentou melhora, com audiometria evidenciando perda sensorioneural leve em orelha direita. Conclusão: A relação entre SS e o uso de IPDE-5 está cada vez mais evidente de acordo com a literatura. É provável que possa haver ativação de vias de estresse celular, contribuindo para patologia.

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Update on the sudden hearing loss

Abstract: sudden hearing loss is defined as a sensory neural hearing deafness of at least 30 dB in three consecutive frequencies yhat as occured within 3 days

Cited by 5 publications

References 23 publications

A polydrug regime for treatment of sudden sensorineural hearing loss

A polydrug regime for treatment of sudden sensorineural hearing loss

Sudden sensorineural hearing loss in children: Our experiences in tertiary care teaching hospital of eastern India

Surdez súbita em paciente em uso de tadalafil: um relato de caso clínico

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