Updated S3 Guideline “Sedation for Gastrointestinal Endoscopy” of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – June 2023 – AWMF-Register-No. 021/014

Wehrmann, Till; Riphaus, Andrea; Eckardt, Alexander J.; Klare, Peter; Kopp, Ina; von Delius, Stefan; Rosien, Ulrich; Tonner, Peter H.; ,

doi:10.1055/a-2165-6388

Cited by 6 publications

(1 citation statement)

References 523 publications

(822 reference statements)

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“… 46 47 The updated guideline of German indicated that patients with ASA class III or higher have an increased risk of complications during sedation. 51 Therefore, the future conclusion of our study should be interpreted with caution.…”

Section: Discussionmentioning

confidence: 83%

Safety and efficacy of remimazolam tosilate combined with low-dose fentanyl for procedural sedation in obese patients undergoing gastroscopy: study protocol for a single-centre, double-blind, randomised controlled trial

Yan,

Wang,

Chen

et al. 2023

BMJ Open

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IntroductionObese patients are susceptible to hypoxaemia during procedural sedation. Propofol combined with low-dose opioids is commonly used as a sedation strategy, but it can exacerbate hypoxaemia by causing cardiopulmonary depression and airway obstruction, especially in obese patients. Remimazolam, a novel ultra-short-acting benzodiazepine, has minimal accumulative effects and less cardiorespiratory depression. This study aims to evaluate the safety and efficacy of combining remimazolam tosilate with low-dose fentanyl as an alternative option for procedural sedation in obese patients undergoing gastroscopy.Methods and analysisThis randomised controlled trial (RCT) will be conducted in the Endoscopy Centre of the First Affiliated Hospital of Xiamen University, recruiting 174 participants scheduled for painless gastroscopy with a body mass index of 30–39.9 kg×m–2. All patients will be randomly divided into two groups in a 1:1 ratio. The sedation strategy of the intervention group is remimazolam tosilate combined with fentanyl, while the control group is propofol combined with fentanyl. The primary outcome is the incidence of hypoxaemia and the secondary outcomes include the time to ambulation, need for airway manoeuvres and rescue sedation, sleep quality, the incidence of sedation failure, adverse events and the cost of sedatives. All statistical tests will be performed using IBM SPSS V.20.0 statistical software. A p value<0.05 is considered statistically significant.Ethics and disseminationThis RCT was reviewed and approved by the Ethics Committee of the First Affiliated Hospital of Xiamen University (Scientific Research Ethics Review 2022, No.093). The results will be published in peer-reviewed journals.Trial registration numberChiCTR2200067076.

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Section: Discussionmentioning

confidence: 83%

Safety and efficacy of remimazolam tosilate combined with low-dose fentanyl for procedural sedation in obese patients undergoing gastroscopy: study protocol for a single-centre, double-blind, randomised controlled trial

Yan,

Wang,

Chen

et al. 2023

BMJ Open

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Analgosedierung für Diagnostik und kleine Eingriffe in der Hämatologie/Onkologie

Röher,

Apostolidou

2024

Pädiatrie up2date

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Eine Vielzahl von diagnostischen und kleineren therapeutischen Eingriffen erfordert eine suffiziente Analgosedierung, um Angst, Schmerzen und Traumatisierung zu verhindern sowie optimale Untersuchungsergebnisse zu gewährleisten. Gerade in der Hämatologie/Onkologie ist nicht nur die Patientensicherheit zu berücksichtigen, sondern auch auf die besonderen Bedürfnisse der Familien und Kinder einzugehen. Beide Aspekte werden in diesem Beitrag betrachtet.

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Sedation practices in Gastrointestinal Endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) survey

Triantafyllou,

Sidhu,

Tham

et al. 2024

Endoscopy

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Updated S3 Guideline “Sedation for Gastrointestinal Endoscopy” of the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) – June 2023 – AWMF-Register-No. 021/014

Cited by 6 publications

References 523 publications

Safety and efficacy of remimazolam tosilate combined with low-dose fentanyl for procedural sedation in obese patients undergoing gastroscopy: study protocol for a single-centre, double-blind, randomised controlled trial

Safety and efficacy of remimazolam tosilate combined with low-dose fentanyl for procedural sedation in obese patients undergoing gastroscopy: study protocol for a single-centre, double-blind, randomised controlled trial

Analgosedierung für Diagnostik und kleine Eingriffe in der Hämatologie/Onkologie

Sedation practices in Gastrointestinal Endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) survey

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