Updates on Lobular Neoplasms and Papillary, Adenomyoepithelial, and Fibroepithelial Lesions of the Breast

Abstract

Context.— This review article is a result of the breast pathology lectures given at the Sixth Chinese American Pathologists Association annual diagnostic pathology course in October 2020 (held virtually due to the coronavirus disease 2019). Objective.— To update recent developments, in this review article, the authors wrote minireviews in the following 4 areas: lobular neoplasm, adenomyoepithelial lesions, papillary lesions, and fibroepithelial lesions. Data Sources.— The sources include extensive literature review, personal research, and experience. Conclusions.— With the wide practice of screening mammography, these lesions are not uncommon in image-guided core biopsies and excisional specimens. Many recent developments have emerged in understanding these lesions. We aim to provide readers with concise updates for each of these lesions with a focus on recent updates in definitions, diagnostic criteria, management, and molecular profiles that are most relevant to the daily practice of pathology and patient management.

Ultrasound‐Guided Vacuum‐Assisted Excision to Treat Intraductal Papilloma

“…Intraductal papillomas are the most common papillary lesions in the breast, which can be divided into central papilloma and peripheral papilloma. Atypical ductal epithelial proliferation may occur in some intraductal papillomas, and these lesions are classified based on its extent as intraductal papilloma with atypical ductal hyperplasia (ADH) or intraductal papilloma with ductal carcinoma in situ (DCIS) [1][2][3][4].…”