2002
DOI: 10.1378/chest.121.5.1531
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Upper Airway Collapsibility During Sleep in Upper Airway Resistance Syndrome

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Cited by 105 publications
(48 citation statements)
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“…These episodes usually occur when the negative pressure of inspiratory muscles exceeds the upper airway dilator muscle activity (critical airway pressure). 19,20 General anesthetics have been shown to decrease the upper airway dilator muscle activity in a dose-dependent manner and thereby increase upper airway collapsibility. [21][22][23] In 12 healthy subjects undergoing minor surgery, increasing depth of propofol anesthesia was associated with a progressive increase in critical airway pressure and upper airway collapsibility.…”
Section: Impact Of Sedation Anesthesia and Opioidsmentioning
confidence: 99%
“…These episodes usually occur when the negative pressure of inspiratory muscles exceeds the upper airway dilator muscle activity (critical airway pressure). 19,20 General anesthetics have been shown to decrease the upper airway dilator muscle activity in a dose-dependent manner and thereby increase upper airway collapsibility. [21][22][23] In 12 healthy subjects undergoing minor surgery, increasing depth of propofol anesthesia was associated with a progressive increase in critical airway pressure and upper airway collapsibility.…”
Section: Impact Of Sedation Anesthesia and Opioidsmentioning
confidence: 99%
“…Consequently, the upper airway soft tissue will be sucked inwards by the negative pressure, resulting in partial or full collapse of the upper airway and episodes of sleep apnea [6,14,15].…”
Section: Discussionmentioning
confidence: 99%
“…The pathogenesis of OSAHS has not been fully defined because of its multifactorial trait. This process is affected by the interaction of many positive and negative factors, such as obesity [1,2], tongue shape [3], tongue volume/oral cavity volume ratio [4], muscular hypotonia of upper airway [5,6], and neck circumference [7,8].…”
Section: Introductionmentioning
confidence: 99%
“…Sujeitos saudáveis apresentam Pcrit -15,4±6,1 cmH2O; sujeitos com síndrome de resistência de VAS, Pcrit -4±2,1 cmH2O; AOS leve/moderada, Pcrit -1,6±2,6 cmH20; e AOS moderada/grave, Pcrit 2,4±2,8 cmH2O. [63] A Pcrit tem sido estudada em diferentes condições. O homem tem uma Pcrit mais positiva que a mulher.…”
Section: Fatores Neuromuscularesunclassified