Upper gastrointestinal abnormalities and <i>Helicobacter pylori</i> in Behçet's disease

Çakmak, Seray Külcü; Çakmak, Atıl; Gül, Ülker; Sulaimanov, Marlen; Bingöl, Pelin; Hazinedaroğlu, M. Selçuk

doi:10.1111/j.1365-4632.2009.04145.x

Cited by 22 publications

(20 citation statements)

References 12 publications

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“…Moreover, endoscopic findings, eradication rate, and prevalence of H. pylori were shown similar in patients with BD and patients in the control group [54]. In another study [55], prevalence of H. pylori was not significantly different in BD patients compared with controls, but the authors believed that HSPs produced by this gastric pathogen might play a role in the pathogenesis of BD.…”

Section: Helicobacter Pylorimentioning

confidence: 86%

Behcet’s disease: from heat shock proteins to infections

2014

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Background: Behcet's disease (BD) is a chronic, inflammatory multisystemic condition of unknown etiology. Although the cause of BD is not clear, it is believed to be the result of an autoimmune process triggered by an infectious or environmental agent (possibly local to a geographic region) in a genetically predisposed individual. Objective: To detail current knowledge of the role of microorganisms in the pathogenesis of BD and review the infectious etiology of this disease. Methods: The review based on publication in SCOPUS, Science direct, and PubMed. Results: A microbial infection has been implicated in the development of the disease to explain the strong inflammatory reactions observed, the activation of monocytes and macrophages, and the induction of proinflammatory cytokines and chemokines detected. Common factors linking some of the possible pathogenetic agents are extrinsically induced tissue stress or heat shock proteins, which react with host tissues and elicit significant T-helper type 1 cell responses. Conclusion: Based on collected data, we conclude that the microorganisms discussed seem to participate and, at least in part, act as triggers during the course of BD. By clarifying the microbial associations of BD and finding its etiology, particularly the causative antigens leading to BD, it would be easier to suggest more effective treatment and preventive strategies for this disease.

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Section: Helicobacter Pylorimentioning

confidence: 86%

Behcet’s disease: from heat shock proteins to infections

2014

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“…Para el desarrollo del cuadro se precisa la oclusión de al menos dos grandes vasos esplácnicos, lo que hace que el mecanismo embólico sea raro, requiriéndose en este caso una obstrucción previa de otra estructura vascular que precipite el proceso. Trastornos vasculíticos o síndromes protrombóticos pueden constituir causas aún más inusuales [3][4][5][6] .…”

Section: Discussionunclassified

Isquemia gástrica fulminante: el estadio final de una enfermedad poco expresiva

Rodríguez‐Perálvarez

Jurado-García

Benitez-Cantero

et al. 2010

Gastroenterología y Hepatología

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“…Non-specific clinical findings may be observed as gastritis and/or gastric ulcer. No statical correlation has been found with helicobacter pylori compared to healthy control group [31]. Isolated ileum involvement is not uncommon [20].…”

Section: Clinical/intestinal Findingsmentioning

confidence: 99%

The Histomorphology of Colonic Behcet's Disease

Baş¹

2017

Gasteroentrol Intest Syst

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Intestinal Behçet's Disease (BD) may manifests with several signs varying from superficial and deep ulcers to massive bleeding and colon perforation. Both mucosal ulcer and inflammation observed as a result of the affected small diameter vessels and ischemic damage findings due to the affected large diameter vessels are significantly associated with morbidity and mortality. In addition, differential diagnosis may be histomorphologically challenging particularly in other diseases involving colon lesions. These histomorphologic findings become important because of the lacking a pathognomonic test for definitive diagnosis. This article discusses histomorphological findings of BD that are much more important in pathology pratics of in addition to epidemiological, etiological and clinical features of the disease.

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Upper gastrointestinal abnormalities and Helicobacter pylori in Behçet's disease

Abstract: Routine endoscopy and screening for H. pylori infection may not be necessary in asymptomatic patients with BD.

Cited by 22 publications

References 12 publications

Behcet’s disease: from heat shock proteins to infections

Behcet’s disease: from heat shock proteins to infections

Isquemia gástrica fulminante: el estadio final de una enfermedad poco expresiva

The Histomorphology of Colonic Behcet's Disease

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