Upper Gastrointestinal Bleeding (Watermelon Stomach) in a Patient With Limited Scleroderma (CREST Syndrome)

Nieves, Ana; Cruz, H. Moruno; Bogado, M.L. Romero; Gómez, A. Pérez

doi:10.1016/j.reumae.2016.05.012

Reumatología Clínica (English Edition)

2017

DOI: 10.1016/j.reumae.2016.05.012

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Upper Gastrointestinal Bleeding (Watermelon Stomach) in a Patient With Limited Scleroderma (CREST Syndrome)

Ana Nieves

H. Moruno Cruz

M.L. Romero Bogado

et al.

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2020

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Cited by 1 publication

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Haematological abnormalities in systemic sclerosis

Wielosz¹,

Majdan²

2020

Reumatologia

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Systemic sclerosis (SSc) is a connective tissue disease characterised by extremely high heterogeneity. This heterogeneity concerns the organ involvement, course of disease and prognosis. Unlike in some other systemic connective tissue diseases, especially systemic lupus erythematosus, in SSc haematological disorders occur rarely. When they develop, they affect erythrocytes, leucocytes and platelets. The most common cause of this pathology of erythrocyte abnormalities is microcytic anaemia resulting from micro-haemorrhages with telangiectasias within the digestive mucosa in patients with SSc. In SSc patients with severe haematological disturbances, the differential diagnosis should include overlapping with another systemic connective tissue disease or a haemato-oncological disease (lympho/myeloproliferative syndrome). In SSc patients with monoclonal proteins or cryoglobulins, it is essential to consider a haemato-oncological disease. In such cases, the differential diagnosis should be focused on a paraneoplastic syndrome, especially when the haematological symptoms develop shortly after the diagnosis of SSc and in the elderly.

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Haematological abnormalities in systemic sclerosis

Wielosz¹,

Majdan²

2020

Reumatologia

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Upper Gastrointestinal Bleeding (Watermelon Stomach) in a Patient With Limited Scleroderma (CREST Syndrome)

Cited by 1 publication

References 8 publications

Haematological abnormalities in systemic sclerosis

Haematological abnormalities in systemic sclerosis

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