Upper Gastrointestinal Tract Alterations in Adenomatosis of the Endocrine Glands

Pluriglandular Syndrome

“…R ecently ad d itio n a l o b se rv a tio n s h av e been recorded. Such a u th o rs as Wermer and Schlaeger and co-workers [18,25] im plied th a t the a lte ra tio n s of th e u p p e r g a s tro in te s tin a l tra c t w ere in tim a te ly re la te d w ith ad en o m atosis o f th e en d o crin e g lands.…”

Pluriglandular Syndrome

“…I n a m ore careful search in th e lite ra tu re , p rio r an d a fte r 1953, th e a u th o r fo u n d 40 a d d itio n al cases w hich in clude th re e in sta n c e s re p o rte d b y 1Vernier [12], fo u r b y M oldawer et al [13], a n d seven by Schlaeger et al [14]. W ith th e five cases p re sen ted here, th is brings th e to ta l to 67 to d ate.…”

“…T h u s W ermer et ul. [12,14] as sociated th e g a stro in te stin a l a lte ra tio n s such as polyposis and peptic u lceratio n s to th is sy n d ro m e.…”

“…O th e r a u th o rs in clu d in g W ermer [12], M oldaiver et al [13] a n d Schlaeger et al [14], ex te n d e d th is in te re stin g sy n d ro m e in to th e o th e r o rg an s and found a te n d e n c y to fam ilial o ccurrence.…”

“…R e c e n tly , a u th o rs h av e em ph asized th e p re p o n d e ra n t role o f p lu ri g la n d u la r sy n d ro m e in g a stro in te stin a l a lte ra tio n s. T h u s, Schlaeger, L e M a y a nd W ermer [14] re p o rte d seven cases o f p lu rig la n d u la r sy n d ro m e in w hich th e g a stro in te stin a l m a n ifestatio n s w ere in tim a te ly * This study is based on personal observations compiled during several years of activity in pathology, both in the United States and abroad, including United States Army; University of California & AEC, San Francisco; Universities of Geneva. Paris and Tehran.…”