Upper Respiratory Tract Allergy

Abstract

Objectives: To evaluate serum vitamin D3, Blood Eosinophils, AbsoluteEosinophils Counts and IgE in the upper respiratory tract allergies (URTA) in Rural PopulationSindh. Study Design: Case control study. Place and Duration: Department of Medicine andBiochemistry, Isra University from January 2014 to October 2015. Subjects & Methods: Asample of 50 diagnosed cases of URTA and 50 age and gender matched control subjects wereselected through non-probability sampling. Blood samples were centrifuged to separate sera.Serum vitamin D3, Blood Eosinophils, Absolute Eosinophils and serum IgE were estimated.Data was analyzed on the SPSS 22.0 software at 95% confidence interval (P≤0.05). Results:Vitamin D3 showed significant decrease in allergic subjects; noted as 26.96±9.75 ng/dlcompared to 32.62±11.75 ng/dl in controls. Blood Eosinophils (%) were raised in the allergicsubjects compared to controls 3.42±1.91 and 1.93±0.65 respectively (p=0.0001). AbsoluteEosinophils counts (AEC) were significantly raised in the allergic cases as shown in Table-I(p=0.0001). Serum IgE in controls and cases was noted as 86.7±17.39 and 400.26±232.8IU/ml respectively (p=0.0001). Conclusion: The present study reports vitamin D3 deficiencyassociated with raised Eosinophils, Absolute Eosinophils counts and serum IgE in upperrespiratory tract allergy.