Urachal Carcinoma: Are Lymphadenectomy and Umbilectomy Necessary?

Jia, Zhuo; Chang, Xiao; Li, Xing; Wang, Qianqian; Zhang, Xu

doi:10.12659/msm.927913

Cited by 10 publications

(20 citation statements)

References 28 publications

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“…The prognostic role of lymph node metastasis in OS has recently been shown [3] , [11] , [13] . However, the therapeutic role of PLND remains controversial, as previous evidence suggests that it does not improve OS, while carrying a higher complication rate and lymph node positivity of only 17% [1] , [2] .…”

Section: Treatmentmentioning

confidence: 99%

“…However, the therapeutic role of PLND remains controversial, as previous evidence suggests that it does not improve OS, while carrying a higher complication rate and lymph node positivity of only 17% [1] , [2] . To the best of our knowledge, PLND is not a predictor of OS; however, the prognostic impact of lymph node metastasis and the accuracy of PLND to assess the pathological stage should encourage clinicians to perform this procedure [11] , [13] . Recent findings confirm the impact of omphalectomy in improving OS and CSS in these patients [11] , [13] .…”

Section: Treatmentmentioning

confidence: 99%

“…To the best of our knowledge, PLND is not a predictor of OS; however, the prognostic impact of lymph node metastasis and the accuracy of PLND to assess the pathological stage should encourage clinicians to perform this procedure [11] , [13] . Recent findings confirm the impact of omphalectomy in improving OS and CSS in these patients [11] , [13] . An umbilical-sparing management approach might be considered in patients with localized disease [14] .…”

Section: Treatmentmentioning

confidence: 99%

See 2 more Smart Citations

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Loizzo

Pandolfo

Crocerossa

et al. 2022

European Urology Open Science

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Section: Treatmentmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Loizzo

Pandolfo

Crocerossa

et al. 2022

European Urology Open Science

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“…Non-glandular neoplasms can be urothelial, squamous cells, neuroendocrine, and mixed type [ 9 ]. Urachal carcinoma affects patients between 40 and 70 years of age, with a male predilection (male: female = 12:1) [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…Regarding urachal tumors, they are associated with a poor prognosis and with a five-year survival rate of between 9 and 50 % [ 10 , 20 , 21 ]. The scarcity of cases and the low number of studies carried out explains the lack of an evidence-based management strategy.…”

Section: Introductionmentioning

confidence: 99%

Urachal Carcinoma, An Unusual Possibility of Hematuria; Case Report and Literature Review

Tiutiuca¹,

Pușcașu

Ţarcă

et al. 2022

Diagnostics

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Urachal cancer is very rare, accounting for only 0.5–2% of bladder-associated malignancies and 0.01% of all cancers in adults. It has an insidious appearance, an aggressive behavior and a poor prognosis. The most common symptoms are hematuria and the presence of a palpable hypogastric mass. The scarcity of cases and the low number of studies carried out explains the lack of an evidence-based management strategy, but it seems that surgical treatment (open, laparoscopy or robot-assisted) represents the gold standard, while neoadjuvant and adjuvant chemotherapy or radiotherapy has a limited impact on overall survival. Since mucinous cystadenocarcinoma of urachal origin is a very uncommon pathological condition the differential diagnosis may be difficult and pathological investigations have to elucidate this disorder. It is worth mentioning the psychological impact on the patient in addition to the medical aspects. A rare condition is associated with heightened risk for mental health and psychosocial difficulties and this must be taken into account in the subsequent follow-up of the patient. In order to increase awareness of this rare entity we report a case of a 40-year-old male with a urachal adenocarcinoma who was treated surgically, with a favorable outcome. We also perform a brief literature review about this type of tumor.

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Hydronephrosis as a Prognostic Factor in Primary Bladder Adenocarcinoma: Insights from a 15-Year Tertiary Center Experience

Suartz,

Neto,

Botelho

et al. 2024

Clinical Genitourinary Cancer

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Urachal Carcinoma: Are Lymphadenectomy and Umbilectomy Necessary?

Cited by 10 publications

References 28 publications

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Current Management of Urachal Carcinoma: An Evidence-based Guide for Clinical Practice

Urachal Carcinoma, An Unusual Possibility of Hematuria; Case Report and Literature Review

Hydronephrosis as a Prognostic Factor in Primary Bladder Adenocarcinoma: Insights from a 15-Year Tertiary Center Experience

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