Urbanization, Life Style Changes and the Incidence/In-Hospital Mortality of Acute Myocardial Infarction in Japan

Age-Specific Trends in the Incidence and In-Hospital Mortality of Acute Myocardial Infarction Over 30 Years in Japan — Report From the Miyagi AMI Registry Study —

“…[18][19][20] In a previous report, we demonstrated the trend for increasing incidence and decreasing in-hospital mortality of AMI from 1979 to 2008 in Japan. 19 Since then, we have been facing rapid social aging in Japan, where such aging should affect the actual situation of cardiovascular diseases, including AMI.…”

“…Indeed, we and others previously reported that the increased prevalence of dyslipidemia in younger patients with AMI was responsible, at least in part, for the increased incidence of AMI in this population. 17, 20 Additionally, the temporal trend in the prevalence of smoking hovered at a high of approximately 40% in male patients and tended to increase in female patients. These results suggest that more strict control of coronary risk factors is needed in young populations to reduce the occurrence of AMI.…”

“…[18][19][20] We revised the registration form occasionally during the 37 years as required. Thus, although the number of incidents of AMI and the basic demographic data (age, sex and time of onset) are available for all patients over the entire period of 37 years, the data regarding prehospital managements, infarction site, coronary risk factors, reperfusion therapies, or in-hospital outcomes were only available for patients registered during the last 10-20 years.…”

“…Fourth, the present study was observational in nature, so the precise mechanisms AMI incidence continued to decline despite increased prevalences of hypertension and dyslipidemia ( Figure 4B). 20 Increased use of antihypertensive agents and statins in the elderly may explain, at least in part, the decline in AMI incidence in this population. 29 In contrast, AMI incidence continues to increase in younger patients aged ≤59 years of both sexes in the past 3 decades.…”

“…[18][19][20] In a previous report, we demonstrated the trend for increasing incidence and decreasing in-hospital mortality of AMI from 1979 Since then, we have been facing rapid social aging in Japan, where such aging should affect the actual situation of cardiovascular diseases, including AMI. Thus, in the present study, we examined the temporal age-specific trends in the incidence and inhospital mortality of AMI during the past 30 years (from 1985 to 2014) in our Miyagi AMI Registry.…”