Uremic pulmonary edema

Rackow, Eric C.; Fein, I. Alan; Sprung, Charles L.; Grodman, Richard

doi:10.1016/0002-9343(78)90466-7

Cited by 48 publications

(25 citation statements)

References 21 publications

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“…Neste estudo, 76 cães apresentaram edema pulmonar. A formação de líquido rico em proteínas nos pulmões de pacientes urêmicos comprova o envolvimento deste mecanismo na patogênese do edema pulmonar (Rackow et al 1978). Pericardite fibrinosa estava presente em somente três dos casos estudados.…”

Section: Discussionunclassified

Epidemiologia e distribuição de lesões extrarrenais de uremia em 161 cães

et al. 2015

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Resumo: Com o objetivo de determinar a epidemiologia e as características morfológicas, incluindo a localização anatômica, das lesões extrarrenais de uremia, bem como determinar as principais lesões do sistema urinário associadas à ocorrência de uremia, foram revisados os protocolos de necropsias de cães realizadas no Laboratório de Patologia Veterinária da Universidade Federal de Santa Maria de janeiro de 1996 a dezembro de 2012 (17 anos). Nesse período foram necropsiados 4.201 cães, sendo que 161 (3,8%) apresentaram lesões extrarrenais de uremia. Em 134 cães (83,2%) foram descritos sinais clínicos associados à uremia. As lesões extrarrenais mais frequentes, em ordem decrescente, foram: gastrite ulcerativa e hemorrágica (56,5%), mineralização de tecidos moles (55,9%), edema pulmonar (47,2%), estomatite e/ou glossite ulcerativa (30,4%), endocardite/trombose atrial e aórtica (28,6%), hiperplasia das paratireoides (9,3%), osteodistrofia fibrosa (8,1%), anemia (6,2%), laringite ulcerativa (5%), enterite ulcerativa/hemorrágica (3,7%), esofagite fibrinonecrótica (1,9%) e pericardite fibrinosa (1.9%). Na maioria dos casos as lesões extrarrenais de uremia foram decorrentes de azotemia prolongada por lesões renais graves, sendo as mais prevalentes a nefrite intersticial e a glomerulonefrite.

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Section: Discussionunclassified

Epidemiologia e distribuição de lesões extrarrenais de uremia em 161 cães

et al. 2015

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“…Clinical or subclinical pulmonary edema and pleural effusions are the most common pulmonary complications. Increased pulmonary capillary hydrostatic pressure due to fluid overload and increased pulmonary capillary permeability are responsible for uremic pulmonary edema [1, 2, 3]. …”

Section: Introductionmentioning

confidence: 99%

The Effect of Renal Transplantation on Pulmonary Function

Kalender¹,

Erk

Pekpak³

et al. 2001

Nephron

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In patients with chronic renal failure, mechanical and hemodynamic changes could occur in the lungs without obvious pulmonary symptoms and findings and their effects could pave the way to pulmonary functional disorders. In this study, pulmonary functional disorders and especially alveolocapillary defects, which are frequently seen in uremia, were determined in renal transplanted patients. Pulmonary functions and diffusion capacity were assessed in uremic patients (n = 20) and in successfully transplanted patients (n = 20) without any lung disease or pulmonary edema symptoms and findings. Patients were selected randomly among outpatients who were followed up in a Nephrology and Transplantation Unit. Forced vital capacity (FVC), forced expiratory volume in 1 s (FEV₁), and peak expiratory flow (PEF_25–75) were measured. Single breath carbon monoxide diffusion test and diffusion lung capacity adjusted for hemoglobin concentration (DLAdj) were done. The means of the spirometric values such as FVC, FEV₁ and FEV₁/FVC were normal in the nondialyzed uremic group, but the PEF_25–75 value (68.7%) and diffusion capacity (DLAdj 72.7%) were found to be slightly low. There were 2 patients with normal values and 18 patients with some functional abnormalities in this nondialyzed uremic group. The means of all spirometric parameters and diffusion capacities were found to be normal in the transplanted group. There were 7 patients with normal function and 13 patients with some functional abnormalities in this transplanted group. When the nondialyzed uremic group and the transplanted group were compared statistically, significant differences were found between their spirometric values (except for FVC) and their diffusion capacities. Even though the uremic patients did not show any symptoms, their pulmonary function tests, especially diffusion capacity, were found to be disturbed. Although the transplanted patients as a group had normal mean spirometric values and diffusion capacity there were nevertheless many individual transplanted patients with defective diffusion capacity and abnormal spirometric values.

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“…Research evidences suggested that restrictive and obstructive lung disease in these patients may attributed to pulmonary hypertension, pulmonary edema, pulmonary fibrosis and calcification, pleural effusion and pleural fibrosis 12,18,19 .…”

Section: Resultsmentioning

confidence: 99%

“…So there may be efflux of protein-rich fluid from the capillaries leading to pulmonary edema. This effect causes increased resistance in the small airways and alveoli which causes narrowing of small airways 18 .…”

Section: Resultsmentioning

confidence: 99%

FVC, FEV1, FEV1/FVC ratio and FEF25-75% in End-stage renal disease (ESRD) patients undergoing maintenance haemodialysis

Hoque

Begum

Latif

et al. 2013

J Bangladesh Soc Physiol

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25-75% were significantly lower in patients except FEV 1 /FVC ratio which was almost similar to control. 63.33% patients had restrictive and 36.67% patients had both restrictive and obstructive (small airway obstruction) feature. Conclusion: This study concluded that some pulmonary functions were markedly reduced in ESRD patients undergoing maintenance haemodialysis. In addition most of the patients were suffering from restrictive and some of them were affected with both obstructive and restrictive type of pulmonary disorders.

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Uremic pulmonary edema

Cited by 48 publications

References 21 publications

Epidemiologia e distribuição de lesões extrarrenais de uremia em 161 cães

Epidemiologia e distribuição de lesões extrarrenais de uremia em 161 cães

The Effect of Renal Transplantation on Pulmonary Function

FVC, FEV1, FEV1/FVC ratio and FEF25-75% in End-stage renal disease (ESRD) patients undergoing maintenance haemodialysis

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