Urinary amylase: Its estimation and significance

The hourly rate of urinary amylase excretion, serum amylase, and serum lipase: Part I In control subjects and patients with renal disease

“…The value of measurements of urinary amylase in the diagnosis of pancreatic disease has long been disputed (von Benczur, 1910;Dozzi, 1940;Sachar, 1952;Saxon, Hinkley, Vogel, andZieve, 1957;Budd, Walter, Harris, and Knight, 1959;Gambill and Mason, 1963). Interpretation and comparison of published results is difficult since there are so many methods of estimation and a variety of ways in which the results can be expressed.…”

LABORATORY PROCEDURES IN THE DIAGNOSIS OF DISEASES OF THE PANCREAS1

“…The methods for determining amylase activity in serum are applicable to urine, but larger quantities of urine than of serum are necessary, because urine has less amylolytic activity than serum. The saccharogenic method, modified (32, 33) to correct for the normal reducing qualities of urine, is the most satisfactory. It is less satisfactory when a marked glycosuria is present, and random specimens may be misleading because of a lack of relationship between the blood and urinary amylase (8, 32, 33, 34).…”

“…The saccharogenic method, modified (32, 33) to correct for the normal reducing qualities of urine, is the most satisfactory. It is less satisfactory when a marked glycosuria is present, and random specimens may be misleading because of a lack of relationship between the blood and urinary amylase (8, 32, 33, 34). The normal range of urinary amylase according to Nothman (35), using the Somogyi saccharogenic method (4), varies from 80 to 350 units per 100 ml.…”

“…The normal range of urinary amylase according to Nothman (35), using the Somogyi saccharogenic method (4), varies from 80 to 350 units per 100 ml. and according to Dozzi (8, 32), also using a saccharogenic method, from 264 to 953 mg. per 100 ml. of urine per twenty‐four hours.…”