2024
DOI: 10.3389/fvets.2024.1362379
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Urinary angiotensin-converting enzyme 2 and its activity in cats with chronic kidney disease

Tzu-Chien Kuo,
Wei-Li Hsu,
Vin-Cent Wu
et al.

Abstract: IntroductionAngiotensin-converting enzyme 2 (ACE2) played an important role in the renin-angiotensin-aldosterone system (RAAS) and it was proved to be renoprotective in renal disease. Urinary angiotensin-converting enzyme 2 (uACE2) has been shown to reflect renal injury in human and experimental studies, but its role in feline kidney disease remains unknown.AimsOur objectives involve comparing uACE2 concentrations and activities in cats across CKD stages with healthy controls, investigating the relationship be… Show more

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