Urinary Potassium Loss in Children With Acute Liver Failure and Acute Viral Hepatitis

Bhatia, Vidyut; Dhawan, Anjali; Arora, Narendra K.; Mathur, Prashant; Das, Manoj; Irshad, Mohammad

doi:10.1097/mpg.0b013e31828fc8ea

Cited by 2 publications

(1 citation statement)

References 20 publications

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“…Nevertheless, no significant differences were found for the VHB patients. Potassium, the main cation in the cell was found to have decreased concentrations in patients with dietar y [7]. Hypokalemia (low serum levels of K) can decrease muscle strength and in severe cases lead to paralysis or cardiac arrhythmia.…”

Section: Serum Parametersmentioning

confidence: 99%

Salivary and Serum Biochemical Alterations in Patients with Acute Viral Hepatitis

Badita¹,

Stanescu²,

Stroescu³

et al. 2018

Rev. Chim.

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Viral hepatitis represents a major health problem worldwide. Approximately 1.4 million people are infected with hepatitis A virus every year, although given that most of the cases evolve asymptomatically the real number could be even higher. At the same time, hepatitis B virus affects up to 30% of the world population and represents one of the main causes of cirrhosis and hepatocellular carcinoma. Thus, it is very important to understand the physiopathology of viral hepatitis A and B not only for the diagnosis, but also for the therapeutic protocol. The present research aimed to determine if HAV and HBV can alter serum and salivary levels of total protein and of 2 important electrolytes: calcium and potassium.

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Section: Serum Parametersmentioning

confidence: 99%

Salivary and Serum Biochemical Alterations in Patients with Acute Viral Hepatitis

Badita¹,

Stanescu²,

Stroescu³

et al. 2018

Rev. Chim.

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Systematic review of the global epidemiology of viral-induced acute liver failure

et al. 2020

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ObjectivesThe aetiology and burden of viral-induced acute liver failure remains unclear globally. It is important to understand the epidemiology of viral-induced ALF to plan for clinical case management and case prevention.ParticipantsThis systematic review was conducted to synthesize data on the relative contribution of different viruses to the aetiology of viral-induced acute liver failure in an attempt to compile evidence that is currently missing in the field. EBSCOhost, PubMed, ScienceDirect, Scopus and Web of Science were searched for relevant literature published from 2009 to 2019. The initial search was run on 9 April 2019 and updated via PubMed on 30 September 2019 with no new eligible studies to include. Twenty-five eligible studies were included in the results of this review.ResultsThis systematic review estimated the burden of acute liver failure after infection with hepatitis B virus, hepatitis A virus, hepatitis C virus, hepatitis E virus, herpes simplex virus/human herpesvirus, cytomegalovirus, Epstein-Barr virus and parvovirus B19. Data were largely missing for acute liver failure after infection with varicella-zostervirus, human parainfluenza viruses, yellow fever virus, coxsackievirus and/or adenovirus. The prevalence of hepatitis A-induced acute liver failur was markedly lower in countries with routine hepatitis A immunisation versus no routine hepatitis A immunisation. Hepatitis E virus was the most common aetiological cause of viral-induced acute liver failure reported in this review. In addition, viral-induced acute liver failure had poor outcomes as indicated by high fatality rates, which appear to increase with poor economic status of the studied countries.ConclusionsImmunisation against hepatitis A and hepatitis B should be prioritised in low-income and middle-income countries to prevent high viral-induced acute liver failure mortality rates, especially in settings where resources for managing acute liver failure are lacking. The expanded use of hepatitis E immunisation should be explored as hepatitis E virus was the most common cause of acute liver failure.RegistrationPROSPERO registration number: CRD42017079730.

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Urinary Potassium Loss in Children With Acute Liver Failure and Acute Viral Hepatitis

Cited by 2 publications

References 20 publications

Salivary and Serum Biochemical Alterations in Patients with Acute Viral Hepatitis

Salivary and Serum Biochemical Alterations in Patients with Acute Viral Hepatitis

Systematic review of the global epidemiology of viral-induced acute liver failure

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