Urinary tract infection caused by Corynebacterium urealyticum in a dog

Abstract

Urinary tract infection (UTI) caused by Corynebacterium urealyticum is a rarely recognised condition in veterinary medicine. This report describes a case in a 13-month-old dog which presented with a history of dysuria and haematuria. C urealyticum was identified as the cause of UTI. The clinical, radiological and ultrasonographic features and the results of urinalysis and urine bacteriological culture are described, as are the therapeutic challenges presented by this particular infection.

Carbonate apatite nephrolithiasis associated withCorynebacterium urealyticumurinary tract infection in a dog

“…[18][19][20] In dogs, only nine cases of C. urealyticum UTIs have been reported, five of which additionally developed encrusted cystitis and/or cystoliths; neither nephrolithiasis nor encrusted pyelitis has been described to date. 1,[4][5][6] Affected dogs were mixed-breeds (German Shepherd Dog × (n = 2), Doberman Pinscher × (1), Alaskan Husky × (1), other (2)) and purebreeds (Doberman Pinscher, Siberian Husky, Bichon Frise, Poodle (1 each)), with a wide age distribution (6 months to 14 years); however, five of the nine dogs were relatively young (≤3 years), as was the dog in the present report. Sex was equally distributed among affected dogs.…”

“…1,[4][5][6] If dogs acquire this infection, the source is usually unknown but is assumed to be from the skin or environmental sources. 4,6 In humans, predisposing factors for C. urealyticum UTIs are previous antibiotic therapy, pre-existing urological diseases or urological procedures. Additionally, immunosuppression as well as chronic debilitating disorders can predispose for the infection.…”

“…U rinary tract infections (UTIs) caused by Corynebacterium urealyticum are uncommon in dogs and cats. [1][2][3][4][5][6] Treatment is difficult because C. urealyticum is usually resistant to most antibacterial drugs and the administration of glycopeptide antibacterial drugs is often necessary for successful elimination of this microorganism. 1,[4][5][6][7][8] If the infection is complicated by the development of encrustations and stones within the urinary tract, acidification of the urine and surgical resection of calcified plaques and uroliths may become necessary.…”

“…[1][2][3][4][5][6] Treatment is difficult because C. urealyticum is usually resistant to most antibacterial drugs and the administration of glycopeptide antibacterial drugs is often necessary for successful elimination of this microorganism. 1,[4][5][6][7][8] If the infection is complicated by the development of encrustations and stones within the urinary tract, acidification of the urine and surgical resection of calcified plaques and uroliths may become necessary. 1,5,6,9 This case report concerns a C. urealyticum UTI associated with bilateral nephrolithiasis in an 11-month-old female spayed mixed-breed dog in which the infection was successfully eliminated and the carbonate apatite (CA) nephroliths dissolved.…”

“…1,[4][5][6][7][8] If the infection is complicated by the development of encrustations and stones within the urinary tract, acidification of the urine and surgical resection of calcified plaques and uroliths may become necessary. 1,5,6,9 This case report concerns a C. urealyticum UTI associated with bilateral nephrolithiasis in an 11-month-old female spayed mixed-breed dog in which the infection was successfully eliminated and the carbonate apatite (CA) nephroliths dissolved.…”