Urine Parameters in Patients with COVID-19 Infection

Morello, Maria; Amoroso, Dominga; Losacco, Felicia; Viscovo, Marco; Pieri, Massimo; Bernardini, Sergio; Adorno, Gaspare

doi:10.3390/life13081640

Cited by 1 publication

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References 69 publications

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“…Proteins in urine, erythrocytes, specific gravity (urine osmolality), nitrites, leukocyte esterase, glucose, ketones, bilirubin, and pH are the typical markers covered by standard commercial sets. Many relevant articles have widely discussed the role and importance of urinalysis for diagnostic purposes [ 1 – 5 ].…”

Section: Introductionmentioning

confidence: 99%

Urine Test Strip Quantitative Assay with a Smartphone Camera

Pohanka,

Zakova

2024

International Journal of Analytical Chemistry

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Urine test strips for urinalysis are a common diagnostic tool with minimal costs and are used in various situations including homecare and hospitalization. The coloration scaled by the naked eye is simple, but it is suitable for semiquantitative analysis only. In this paper, a colorimetric assay is developed based on a smartphone digital camera and urine test strips. Assays of pH, albumin, glucose, and lipase activity were performed as a tool for the diagnosis of aciduria, alkaluria, glycosuria, proteinuria, and leukocyturia. The RGB color channels were analyzed in the colorimetric assay, and the assay exerted good sensitivity, and all the particular diagnoses proved to be reliable. The limits of detection for glucose (0.11 mmol/L), albumin (0.15 g/L), and lipase (2.50 U/μL) were low enough to cover the expected physiological concentration, and the range for pH was also satisfactory. The urine test strips with a camera as an output detector proved applicability to spiked urine samples, and the results were also well in comparison to the standard assays which confirms the practical relevance of the presented findings.

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Section: Introductionmentioning

confidence: 99%