Use of imaging techniques for melanocytic naevi and basal cell carcinoma in integrative analysis (Review)

A compact handheld skin ultrasound imaging device has been developed that uses co-registered optical and ultrasound imaging to provide diagnostic information about the full skin depth. The aim of the current work is to present the preliminary clinical results of this device. Using additional photographic, dermoscopic and ultrasonic images as reference, the images from the device were assessed in terms of the detectability of the main skin layer boundaries and characteristic image features. Combined optical-ultrasonic recordings of various types of skin lesions (melanoma, basal cell carcinoma, seborrheic keratosis, dermatofibroma, naevus, dermatitis and psoriasis) were taken with the device (N = 53) and compared with images captured with a reference portable skin ultrasound imager. The investigator and two additional independent experts performed the evaluation. The detectability of skin structures was over 90% for the epidermis, the dermis and the lesions. The morphological and echogenicity information observed for the different skin lesions were found consistent with those of the reference ultrasound device and relevant ultrasound images in the literature. The presented device was able to obtain simultaneous in-vivo optical and ultrasound images of various skin lesions. This has the potential for further investigations, including the preoperative planning of skin cancer treatment.

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Section: Melanomasupporting

confidence: 94%

“…It appears as a hypoechoic, heterogeneous lesion in the deeper parts of the dermis, with irregular borders and asymmetric shape. These observations are in correspondence with those found in the literature [36]. (b) In the case of melanoma metastasis, no characteristic features can be observed in the optical images of the skin surface.…”

Section: Melanomasupporting

confidence: 91%

Preliminary Clinical Experience with a Novel Optical–Ultrasound Imaging Device on Various Skin Lesions

et al. 2022

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“…Agreement was reached through discussion if any discordance occurred. Refer to the previous reports, 9,10,12 each observer was asked to analyze all the ultrasound images and to describe the following features: morphological flatness (flat, uneven), location of the lesion within the skin layers (epidermis, dermis, or both), shape (oval or strip), boundary (clear or unclear), internal echogenicity (homogeneous or heterogeneous), hyperechoic spots (presence or absence), lateral acoustic shadow (presence or absence), posterior echoic patterns(attenuated or absence), mushroom sign (presence or absence), straw‐hat sign(presence or absence). Straw‐hat sign consisted of a brim (a strip‐like hypoechoic area beneath the epidermis) and a cap (elevated hypoechoic area above the epidermis).…”

Section: Methodsmentioning

confidence: 99%

A comparative study of melanocytic nevi classification with dermoscopy and high‐frequency ultrasound

Wang

Gao

Liu

et al. 2021

Skin Research and Technology

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Background: Melanocytic nevi (MN) can be classified into three subtypes according to the depth of the nests of nevus cells which is important for management. Highfrequency ultrasound (HF-US) can clearly reveal the lesion size, contour, depth, and internal structures. However, the HF-US studies of MN according to subtypes are limited. We aimed to describe the HF-US features of MN and explore its value in accurate classification. Materials and methods:This retrospective study was conducted from January 2018 to November 2019. Eighty-five patients with MN were included and examined by 50 and 20 MHz HF-US. The HF-US features were recorded including morphological flatness, depth, shape, boundary, internal echogenicity, hyperechoic spots, lateral acoustic shadow, posterior echoic patterns, mushroom signs, and straw-hat signs. Each image was evaluated by two physicians independently, and the consistency was tested.Results: Eleven lesions could not be detected by HF-US. The rest 74 lesions underwent ultrasonic analysis. MN appeared as strip-shaped or oval, hypoechoic areas localized in the epidermis and dermis under ultrasonography. A strong consistency between HF-US and dermoscopy of determining the lesion depth was achieved (κ = 0.935, p < 0.001).The hyperechoic spots were found in 57.6% intradermal nevi. The mushroom signs were seen in 34.8% intradermal nevi, and the straw-hat signs were seen in all the compound nevi. Conclusion:MN can be correctly classified using HF-US, and it had a strong correlation with dermoscopic and clinical classification. HF-US could further reveal the internal morphological features of MN, which may support more precise classification and management.

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“…These hyperechoic spots can help distinguish BCC from other types of skin tumors. [ 18 ] KA generally has a clear boundary and a regular shape. On CT, BCC has equal or low density relative to the adjacent muscle tissue.…”

Section: Resultsmentioning

confidence: 99%

The diagnostic value of imaging techniques for keratoacanthoma: A review

et al. 2022

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Keratoacanthoma (KA) is a fast-growing skin tumor with solitary KA being the most common type. KAs rarely metastasize and subside spontaneously. Although histopathology is the gold standard for the diagnosis of KA, its histopathological features are sometimes difficult to distinguish from those of other skin tumors. Imaging studies have certain advantages in the preoperative diagnosis of KA; they not only show the exact shape of the lesion but can also accurately determine the extent of the lesion. Combined with histopathological examination, these findings help establish a diagnosis. By summarizing the imaging features of KA, this article aimed to improve radiologists’ understanding of the disease and help in the clinical and differential diagnosis of KA.

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Use of imaging techniques for melanocytic naevi and basal cell carcinoma in integrative analysis (Review)

Cited by 14 publications

References 65 publications

Preliminary Clinical Experience with a Novel Optical–Ultrasound Imaging Device on Various Skin Lesions

Preliminary Clinical Experience with a Novel Optical–Ultrasound Imaging Device on Various Skin Lesions

A comparative study of melanocytic nevi classification with dermoscopy and high‐frequency ultrasound

The diagnostic value of imaging techniques for keratoacanthoma: A review

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