“…We demonstrated the excellent safety of AF CA on uninterrupted DOAC regimen without imaging for LA thrombus in a carefully selected population with paroxysmal AF displaying low thromboembolic risk (mean CHA 2 DS 2 -VASc score of 1.4 ± 1.2) and absence of significant LA enlargement. Based on our findings, patients without risk factors for the presence of LA thrombus such as persistent AF, structural heart disease, and dilated LA, 2,3,5,6,[12][13][14] can safely undergo AF CA without pre-or peri-procedural imaging.…”