Usefulness of Iterative Reconstruction Method in the Field of Acute Cerebral Infarction Computed Tomography Examination

Abstract

We evaluated clinical images to investigate the usefulness of adaptive iterative dose reduction algorithm (AIDR) in the field of acute cerebral infarction. We did receiver operating characteristic (ROC) analysis by 4 radiologists using 50 clinical images (abnormal case=24, normal case=26) which were reconstructed by AIDR and filtered back projection (FBP). The area under the curve (AUC) value from average ROC curve of observers were 0.79 with the FBP and 0.87 with the AIDR (P=0.31). The standard deviation of AUC was 0.06 with the FBP and 0.03 with the AIDR. More in detail, the AUC value of Expert group (over 10 years of experience) increased to 0.06 by using AIDR compared with FBP method. On the other hand, in Beginner group (less than 10 years of experience) there was 0.09 increase. Therefore, there was some possibility to reduce the variation of diagnostic accuracy among observer and the diagnostic accuracy improvement of the doctor in a few Experience group, by using AIDR for acute cerebral infarction computed tomography (CT) examination.

Computed tomography (CT) imaging evaluation of integrated traditional Chinese medicine cooperative therapy in treating acute cerebral infarction

“…Studies have shown that traditional Chinese herbal medicines has the effects of increasing high-density lipoprotein, reducing low-density lipoprotein, regulating blood lipids, stabilizing plaque, and protecting vascular endothelium. [ 19 – 21 ] In addition, in the early stages of ACI, Chinese herbal medicines can remove free radicals and reduce damage caused by free radicals. [ 22 , 23 ] This can reduce blood viscosity, thereby improving the oxygen carrying capacity of red blood cells and preventing brain tissue damage.…”

Sequential butylphthalide therapy combined with dual antiplatelet therapy in the treatment of acute cerebral infarction

“…1 ACI, also known as ischemic stroke, is caused by blood supply disorders induced by various reasons in regional brain tissue, leading to necrosis of ischemic and hypoxic lesions in brain tissues and the clinical neurological deficits, 2,3 ACI may cause limb function and language dysfunction and can also affect cognitive function of patients in varying degrees, manifested as mental and behavioral abnormalities, apraxia, agnosia, loss of understanding and so on, and it will cause serious harm to patients' lives and living quality. 4,5 ACI patients are often treated symptomatically by expanding blood volume, reducing intracranial pressure, anticoagulating and controlling basic diseases. However, in recent years, with the change of people's lifestyle, the etiology of ACI is complex and diverse, and the effect of conventional treatment is poor.…”