Usefulness of tissue Doppler imaging for estimation of left ventricular filling pressures in patients with systolic and diastolic heart failure

The relationship between BNP and E/Ea in patients hospitalized with acute heart failure

“…Although much data supports a close relationship between BNP-32, NT-proBNP and E/Ea in patients with acute decompensated HF [1,[4][5][6][8][9][10][11][13][14][15], the association between changes in BNP-32 or NT-proBNP levels and E/Ea is uncertain. A recent study describes changes in E/Ea and BNP-32, compared to changes in PCWP in 9 patients admitted to an intensive care unit and suggested that temporal changes in PCWP were 'tracked' by changes in both E/Ea and BNP-32 [1], however the generalizability of this data outside of intensive care is uncertain.…”

“…BNP and E/Ea are both closely related to left ventricular filling pressure in patients with heart failure (HF) [1][2][3][4][5][6] and have similar diagnostic [7][8][9][10][11] and prognostic [12][13][14][15][16] utility. Most of the literature exploring the relationship between natriuretic peptides and E/Ea in HF patients is related to single measurements.…”

Comparison of the reliability of E/E′ to estimate pulmonary capillary wedge pressure in heart failure patients with preserved ejection fraction versus those with reduced ejection fraction

“…The results of previous studies into the relationship between mitral E/E 0 and PCWP are contentious, with some studies showing good correlations between E/E 0 and PCWP HFpEF heart failure with preserved ejection fraction, HFrEF, heart failure with reduced ejection fraction, NPV negative predictive value, PCWP pulmonary capillary wedge pressure, PPV positive predictive value Abbreviations as in Table 2 Int J Cardiovasc Imaging in systolic and diastolic heart failure [3,8,9], but others failing to find any correlation between mitral E/E 0 and PCWP in either advanced systolic dysfunction or healthy volunteers [10,11]. These discrepancies may be related to the different clinical situations in these studies.…”

“…However, the results of previous studies into the relationship between mitral E/E 0 and PCWP are contentious. For example, several studies have reported that E/E 0 correlates well with PCWP in systolic and diastolic heart failure [3,8,9], whereas, others have not found any correlation between mitral E/E 0 and PCWP in either advanced systolic dysfunction or healthy volunteers [10,11]. Therefore, assessing the diagnostic usefulness of mitral E/E 0 in estimating PCWP is an important topic for research.…”

Different prognostic impact of the tissue Doppler-derived E/e′ ratio on mortality in Chagas cardiomyopathy patients with heart failure

“…In particular, the ratio of early transmitral velocity to tissue Doppler mitral annular early diastolic velocity (E/e=) has become an accepted non-invasive method to estimate LV filling pressures in a variety of cardiac diseases. [13][14][15] However, the accuracy of the E/e= ratio for the prediction of LV filling pressure has recently been questioned in hypertrophic 16 and in dilated cardiomyopathy. 17 Several studies have shown that the E/e= ratio is a powerful predictor of adverse outcome in patients with heart failure.…”